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Rabbit Anti-GBAS antibody
Rabbit Anti-GBAS antibody
4 nitrophenylphosphatase domain and non neuronal SNAP25 like 2; gbas; Glioblastoma amplified sequence; Glioblastoma-amplified sequence; NIPS2_HUMAN; Nipsnap homolog 2; NipSnap2; Protein NipSnap homolog 2.
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  • NO.:SL13299R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Chicken,Cow,Horse,Rabbit,Sheep,)
    Applications:WB ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Details

Product Name GBAS
Chinese Name 胶质母细胞瘤相关蛋白GBAS抗体
Alias 4 nitrophenylphosphatase domain and non neuronal SNAP25 like 2; gbas; Glioblastoma amplified sequence; Glioblastoma-amplified sequence; NIPS2_HUMAN; Nipsnap homolog 2; NipSnap2; Protein NipSnap homolog 2.  
Research Area Tumour  Cell biology  Neurobiology  Signal transduction  Transporter  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Chicken, Cow, Horse, Rabbit, Sheep, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 34kDa
Cellular localization cytoplasmic The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human GBAS: 21-120/286 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail NIPSNAP2 is a 286 amino acid protein that is abundantly expressed in heart and skeletal muscle. Belonging to the NIPSNAP family, NIPSNAP2 may be involved in vesicular transport. NIPSNAP2 contains a signal peptide, a transmembrane domain and two tyrosine phosphorylation sites. NIPSNAP2 is encoded by a gene mapping to human chromosome 7p11.2. Chromosomal region 7p12 is amplified in approximately 40% of glioblastomas, the most common and malignant form of central nervous system tumor. Human chromosome 7 houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.

Tissue Specificity:
Widely expressed. Most abundant in heart and skeletal muscle.

Similarity:
Belongs to the NipSnap family.

SWISS:
O75323

Gene ID:
2631

Database links:

Entrez Gene: 2631 Human

Entrez Gene: 14467 Mouse

Entrez Gene: 498174 Rat

Omim: 603004 Human

SwissProt: O75323 Human

SwissProt: O55126 Mouse



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