Product Name	Parvalbumin
Chinese Name	细小清蛋白抗体
Alias	D22S749; MGC116759; Parvalbumin alpha; PRVA_HUMAN; PVALB.
literatures	Specific References  (2)     |     SL1299R has been referenced in 2 publications. [IF=2.21] Qi et al. Interaction of basolateral amygdala, ventral hippocampus and medial prefrontal cortex regulates the consolidation and extinction of social fear. (2018) Behav.Brain.Funct. 14:7  other ;  Mouse.   PubMed:29554926 [IF=1.68] Chen J et al. Morphology of Inner Retina in Rhesus Monkeys of Various Ages: A Comparative Study.J Ophthalmol. 2019 Mar 3;2019:7089342.  IF ;  Monkey.   PubMed:30944733
Research Area	Neurobiology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Mouse, Rat,  (predicted: Chicken, Pig, Cow, Horse, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/Test IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	12kDa
Cellular localization	The nucleus Extracellular matrix
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Parvalbumin: 7-110/110
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The protein encoded by this gene is a high affinity calcium ion-binding protein that is structurally and functionally similar to calmodulin and troponin C. The encoded protein is thought to be involved in muscle relaxation. Belongs to the parvalbumin family. Contains 2 EF-hand domains. This protein binds two calcium ions. Function: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions. Similarity: Belongs to the parvalbumin family. Contains 2 EF-hand domains. SWISS: P20472 Gene ID: 5816 Database links: Entrez Gene: 396459 Chicken Entrez Gene: 396531 Chicken Entrez Gene: 5816 Human Entrez Gene: 19293 Mouse Entrez Gene: 25269 Rat Omim: 168890 Human SwissProt: P20472 Human SwissProt: P32848 Mouse SwissProt: P02625 Rat Unigene: 295449 Human Unigene: 2766 Mouse Unigene: 2005 Rat (Parvalbumin, PV)细小白蛋白属于钙Binding protein家族,是一种细胞内可溶的小Binding protein，过去曾认为，仅出现在哺乳动物某些肌纤维内,它与Ca2+有高度亲合力,与钙调蛋白竞争自由Ca2+,故可阻止肌浆内的Ca2+增高，可抗衡细胞内钙过量的发生。
Product Picture	Sample: Lane 1: Mouse Kidney tissue lysates Lane 2: Rat Kidney tissue lysates Primary: Anti-Parvalbumin (SL1299R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 12 kDa Observed band size: 10 kDa Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by microwave in sodium citrate buffer (pH6.0) ; Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (3% BSA) at RT for 30min; Antibody incubation with (Parvalbumin) Polyclonal Antibody, Unconjugated (SL1299R) at 1:400 overnight at 4℃, followed by conjugation to the secondary antibody (labeled with HRP)and DAB staining. Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by microwave in sodium citrate buffer (pH6.0) ; Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (3% BSA) at RT for 30min; Antibody incubation with (Parvalbumin) Polyclonal Antibody, Unconjugated (SL1299R) at 1:400 overnight at 4℃, followed by conjugation to the secondary antibody (labeled with HRP)and DAB staining.

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