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Product Name APMAP Chinese Name 脂肪The cell membrane相关蛋白抗体 Alias Adipocyte plasma membrane associated protein; Adipocyte plasma membrane-associated protein; apmap; APMAP_HUMAN; BSCv; BSCv protein; C20orf3; Chromosome 20 open reading frame 3; Protein BSCv. Research Area Tumour Cell biology Signal transduction The new supersedes the old Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Monkey, ) Applications WB=1:500-2000 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 46kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human APMAP: 151-250/416 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail APMAP is a 416 amino acid single-pass type II membrane protein that belongs to the strictosidine synthase family and is thought to play a role in adipocyte differentiation. The gene encoding C20orf3 maps to human chromosome 20, which houses over 600 genes some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception.
Function:
Exhibits strong arylesterase activity with beta-naphthyl acetate and phenyl acetate. May play a role in adipocyte differentiation.
Subcellular Location:
Membrane.
Tissue Specificity:
Liver, glomerular and tubular structures of the kidney, endothelial cells, arterial wall and pancreatic islets of Langerhans (at protein level). Found ubiquitously in adult as well as in embryonic tissues. In adult tissue, the highest expression is found in the liver, placenta and heart. Found on the cell surface of monocytes. In embryonic tissue, the highest expression levels is found in the liver and the kidney.
Similarity:
Belongs to the strictosidine synthase family.
SWISS:
Q9HDC9
Gene ID:
57136
Database links:Entrez Gene: 57136 Human
Entrez Gene: 71881 Mouse
Omim: 615884 Human
SwissProt: Q9HDC9 Human
SwissProt: Q9D7N9 Mouse
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