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Product Name LRRC25 Chinese Name 富含亮氨酸重复蛋白25抗体 Alias FLJ38116; Leucine rich repeat containing 25; Leucine rich repeat containing protein 25; LRRC 25; MAPA; Monocyte and plasmacytoid activated molecule; LRC25_HUMAN. Research Area Cell biology immunology Developmental biology Stem cells lymphocyte b-lymphocyte Immunogen Species Rabbit Clonality Polyclonal React Species Human, Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 31kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human LRRC25: 81-180/305 <Extracellular> Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail LRRC25 is a 305 amino acid protein that contains two LRR repeats. LRRC25 is a single-pass type I membrane protein that is expressed in monocyte-derived dendritic cells (MDDC), granulocytes, monocytes, plasmacytoid dendritic cells (PDC), B-lymphocytes, peripheral blood leukocytes, spleen and bone marrow, with lower levels in lymph nodes, fetal liver, and appendix. LRRC25 may play a role in the activation of cells of innate and acquired immunity.
Function:
LRRC25 is a single-pass type I membrane protein. It contains 2 LRR (leucine-rich) repeats. LRRC25 may be involved in the activation of cells of innate and acquired immunity.
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Tissue Specificity:
Expressed in plasmacytoid dendritic cells (PDC), monocyte-derived dendritic cells (MDDC), granulocytes, monocytes, B-lymphocytes, peripheral blood leukocytes, spleen, bone marrow, and, to a lesser extent, lymph nodes, fetal liver, and appendix but not in thymus.
SWISS:
Q8N386
Gene ID:
126364
Database links:Entrez Gene: 126364 Human
Omim: 607518 Human
SwissProt: Q8N386 Human
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