Product Name	ZFX
Chinese Name	Zinc finger proteinX染色体蛋白抗体
Alias	X-linked zinc finger protein; zfx; ZFX_HUMAN; Zinc finger protein, X-linked; Zinc Finger X Chromosomal Protein; Zinc finger X-chromosomal protein.
literatures	Specific References  (2)     |     SL12306R has been referenced in 2 publications. [IF=2.886] Jiancong Lu. et al. Circ_0020123 Increases ZFX Expression to Facilitate Non-Small Cell Lung Cancer Progression by Sponging miR-142-3p. Cancer Manag Res. 2021; 13: 1687–1698  WB ;  Human.   PubMed:33633466 [IF=1.706] Yang et al. Zinc finger protein x-linked (ZFX) contributes to patient prognosis, cell proliferation and apoptosis in human laryngeal squamous cell carcinoma. (2016) Int.J.Clin.Exp.Pathol. 8:13886-99  IHC ;  Human.   PubMed:26823701
Research Area	Cell biology  Developmental biology  Signal transduction  Stem cells  Zinc finger protein  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Rat, Dog, Cow, Sheep, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	90kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human ZFX: 401-500/805
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zfy1 (zinc finger protein 1, Y linked), also known Zfy-1 is a 782 amino acid nuclear protein belonging to the Krüppel C2H2-type zinc-finger protein family and the ZFX/ZFY subfamily. Containing thirteen C2H2-type zinc fingers, Zfy1 is expressed in the genital ridge and adult testis and may be a probable transcription activator. The gene encoding Zfy1 maps to mouse chromosome Y. Function: Probable transcriptional activator. Subcellular Location: Nucleus. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. ZFX/ZFY subfamily. Contains 13 C2H2-type zinc fingers. SWISS: P17010 Gene ID: 7543 Database links: Entrez Gene: 7543 Human Omim: 314980 Human SwissProt: P17010 Human Unigene: 336681 Human
Product Picture	Tissue/cell: human lung carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-ZFX Polyclonal Antibody, Unconjugated(SL12306R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

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