Product Name	GGNBP1
Chinese Name	配子生成素Binding protein1抗体
Alias	Gametogenetin-binding protein 1; GGNBP1; Putative gametogenetin-binding protein 1; GGNB1_HUMAN.
Research Area	Cell biology  Developmental biology  Stem cells
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	12kDa
Cellular localization	cytoplasmic The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from Human GGNBP1: 25-109/109
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	GGNBP1 is a 109 amino acid protein that is thought to be involved in spermatogenesis and interacts with gametogenetin. GGNBP1 localizes to cytoplasm, membrane and Golgi apparatus, and exits as two isoforms which are produced by alternative splicing events. The gene encoding GGNBP1 maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6. Function: May be involved in spermatogenesis. Subunit: Interacts with GGN (By similarity). Subcellular Location: Cytoplasm. Membrane; Peripheral membrane protein. Golgi apparatus SWISS: Q5YKI7 Gene ID: 449520 Database links: Entrez Gene: 449520 Human Omim: 609495 Human SwissProt: Q5YKI7 Human Unigene: 582973 Human

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