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Rabbit Anti-FUT2 antibody
Rabbit Anti-FUT2 antibody
Fucosyltransferase 2; Se; SE2; SEC2; Secretor factor;FUT2_HUMAN.
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  • NO.:SL12258R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Human,(predicted: Mouse,Rat,Pig,Cow,Horse,Rabbit,Sheep,)
    Applications:WB ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Details

Product Name FUT2
Chinese Name 岩藻糖转移酶2抗体
Alias Fucosyltransferase 2; Se; SE2; SEC2; Secretor factor;FUT2_HUMAN.  
literatures
Specific References  (1)     |     SL12258R has been referenced in 1 publications.
[IF=7.464] Zhengchang Wu. et al. Insight into mechanisms of pig lncRNA FUT3-AS1 regulating E. coli F18-bacterial diarrhea. PLOS PATHOG. 2022 Jun;18(6):e1010584  WB ;  Pig.  
Research Area Tumour  Cell biology  immunology  Signal transduction  The new supersedes the old  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human,  (predicted: Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 39kDa
Cellular localization cytoplasmic The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from Human FUT2: 231-343/343 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble A and B antigen synthesis pathway. H and Se enzymes fucosylate the same acceptor substrates but exhibit different Km values. FUT2 is expressed on the surface of several human tumor cell lines such as BEL-7404, SPC-A-1, and SGC-7901.

Function:
Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble A and B antigen synthesis pathway. H and Se enzymes fucosylate the same acceptor substrates but exhibit different Km values.

Subcellular Location:
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.

Tissue Specificity:
Small intestine, colon and lung.

Similarity:
Belongs to the glycosyltransferase 11 family.

SWISS:
Q10981

Gene ID:
2524

Database links:

Entrez Gene: 2524 Human

Entrez Gene: 14344 Mouse

Omim: 182100 Human

SwissProt: Q10981 Human

SwissProt: Q9JL27 Mouse

Unigene: 579928 Human

Unigene: 290046 Mouse



Product Picture
Sample:
SW480(Human) Cell Lysate at 30 ug
HepG2(Human) Cell Lysate at 30 ug
Primary: Anti- FUT2 (SL12258R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 39 kD
Observed band size: 54 kD

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