Product Name	ZIC5
Chinese Name	Zinc finger proteinZIC5抗体
Alias	zic5; ZIC5_HUMAN; Zinc finger protein of the cerebellum 5; Zinc finger protein ZIC 5.
literatures	Specific References  (2)     |     SL12147R has been referenced in 2 publications. [IF=7.109] Tan, Yi-Fan. et al. AR-regulated ZIC5 contributes to the aggressiveness of prostate cancer. CELL DEATH DISCOV. 2022 Sep;8(1):1-15  IHC, WB ;  Human.   PubMed:36127329 [IF=2.456] Han W et al. Clinicopathologic and Prognostic Significance of the Zinc Finger of the Cerebellum Family in Invasive Breast Cancer.J Breast Cancer. 2018 Mar;21(1):51-61.  IHC ;  Human.   PubMed:29628984
Research Area	Cell biology  Neurobiology  Signal transduction  transcriptional regulatory factor  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Cow, Horse, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	68kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human ZIC5: 501-600/663
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Zic5 (zinc finger protein of the cerebellum 5) is a C2H2 zinc finger transcription factor that influences development of the neural crest. Zic family members are abundant in developing and adult cerebellum. Zic family members are important during development, and have been associated with X-linked visceral heterotaxy and holoprosencephaly type 5. Zic5 is closely linked to Zic2, a related family member on chromosome 13. Function: Essential for neural crest development, converting cells from an epidermal fate to a neural crest cell fate. Binds to DNA. Subcellular Location: Nucleus. Similarity: Belongs to the GLI C2H2-type zinc-finger protein family. Contains 4 C2H2-type zinc fingers. SWISS: Q96T25 Gene ID: 85416 Database links: Entrez Gene: 85416 Human Entrez Gene: 65100 Mouse Entrez Gene: 361095 Rat SwissProt: Q96T25 Human SwissProt: Q7TQ40 Mouse Unigene: 508570 Human Unigene: 390761 Mouse Unigene: 198356 Rat

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