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Rabbit Anti-5HT7 Receptor antibody
Rabbit Anti-5HT7 Receptor antibody
SR-7; HT 7; 5 HT X; 5 hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase coupled); 5 hydroxytryptamine (serotonin) receptor 7; 5 hydroxytryptamine receptor 7; 5-HT-7; 5-HT-X; 5-HT7; 5-hydroxytryptamine receptor 7; 5HT7; 5HT7R_HUMAN; HTR7; Seroton
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  • NO.:SL12056R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Mouse,Rat,(predicted: Human,)
    Applications:WB ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Product Name 5HT7 Receptor
Chinese Name 5-羟色胺受体7抗体
Alias SR-7; HT 7; 5 HT X; 5 hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase coupled); 5 hydroxytryptamine (serotonin) receptor 7; 5 hydroxytryptamine receptor 7; 5-HT-7; 5-HT-X; 5-HT7; 5-hydroxytryptamine receptor 7; 5HT7; 5HT7R_HUMAN; HTR7; Serotonin 5 HT 7 receptor; Serotonin receptor 7.  
Research Area Neurobiology  The cell membrane受体  G protein-coupled receptor  The new supersedes the old  G protein signal  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Mouse, Rat,  (predicted: Human, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 54kDa
Cellular localization The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human 5HT7 Receptor/SR-7: 51-150/479 <Extracellular>
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail The neurotransmitter, serotonin, is thought to play a role in various cognitive and behavioral functions. The serotonin receptor encoded by this gene belongs to the superfamily of G protein-coupled receptors and the gene is a candidate locus for involvement in autistic disorder and other neuropsychiatric disorders. Three splice variants have been identified which encode proteins that differ in the length of their carboxy terminal ends. [provided by RefSeq, Jul 2008]

Function:
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Isoform A is the predominant isoform in spleen, caudate and hippocampus.
Isoform B is expressed at lower levels. Isoform D is a minor isoform in term of expression.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
P34969

Gene ID:
3363

Database links:

Entrez Gene: 3363 Human

Entrez Gene: 15566 Mouse

Entrez Gene: 65032 Rat

Entrez Gene: 100135549 Guinea pig

Omim: 182137 Human

SwissProt: P50407 Guinea pig

SwissProt: P34969 Human

SwissProt: P32304 Mouse

SwissProt: P32305 Rat

Unigene: 73739 Human

Unigene: 254266 Mouse

Unigene: 87132 Rat



Product Picture
Sample:
Lane 1: Mouse Cerebrum tissue lysates
Lane 2: Mouse Cerebellum tissue lysates
Lane 3: Rat Cerebrum tissue lysates
Lane 4: Rat Cerebellum tissue lysates
Primary: Anti-5HT7 Receptor (SL12056R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 54 kDa
Observed band size: 50 kDa
Sample:
Hippocampus (Mouse) Lysate at 40 ug
Hippocampus(Rat) Lysate at 40 ug
Primary: Anti- 5HT7 Receptor (SL12056R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 54 kD
Observed band size: 54 kD

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