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Rabbit Anti-Cyclin M3 antibody
Rabbit Anti-Cyclin M3 antibody
ACDP3; Ancient conserved domain containing protein 3; CNNM3; DKFZp434I1016; FLJ20018; Metal transporter CNNM3; CNNM3_HUMAN.
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  • NO.:SL12045R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,)
    Applications:WB ELISA
    concentration:1mg/ml
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Details

Product Name Cyclin M3
Chinese Name 周期素M3抗体
Alias ACDP3; Ancient conserved domain containing protein 3; CNNM3; DKFZp434I1016; FLJ20018; Metal transporter CNNM3; CNNM3_HUMAN.  
Research Area Cell biology  immunology  Signal transduction  Cyclin  Channel protein  The cell membrane蛋白  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, )
Applications WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 76kDa
Cellular localization cytoplasmic The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human Cyclin M3: 251-350/707 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Cyclin M3 is a 707 amino acid multi-pass membrane protein that shares weak sequence similarity with cyclin proteins, yet displays no cyclin-like function in vivo. Though ubiquitously expressed, Cyclin M3 is found at highest levels in kidney, brain, spleen and heart. Cyclin M3 is localized to the nucleus where it is likely a metal transporter. Cyclin M3 contains two CBS domains, which appear to bind ligands with an adenosyl group such as AMP, ATP and S-AdoMet and may play a regulatory role in sensitizing proteins to adenosyl-carrying ligands. There are three isoforms of Cyclin M3 that are produced as a result of alternative splicing events.

Function:
Cyclin M3 is a probable metal transporter. There are three named isoforms.

Subcellular Location:
Integral to plasma membrane; Multi-pass membrane protein

Tissue Specificity:
Widely expressed. Expressed at higher level in heart and spleen.

Similarity:
Belongs to the ACDP family.
Contains 2 CBS domains.
Contains 1 DUF21 domain.

SWISS:
Q8NE01

Gene ID:
26505

Database links:

Entrez Gene: 26505 Human

Entrez Gene: 94218 Mouse

Entrez Gene: 301345 Rat

Omim: 607804 Human

SwissProt: Q8NE01 Human

SwissProt: Q32NY4 Mouse

Unigene: 711617 Human



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