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Rabbit Anti-GPR102 antibody
Rabbit Anti-GPR102 antibody
G protein coupled receptor 102; G-protein coupled receptor 102; GPR102; TA5; TAAR8; TAAR8_HUMAN; TaR-5; TaR-8; TAR5; Trace amine assiciated receptor 8; Trace amine receptor 5; Trace amine receptor 8; Trace amine-associated receptor 8; TRAR5; GPCR GPR102.
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  • NO.:SL12023R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Pig,Cow,Rabbit,Sheep,)
    Applications:WB ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
  • Goods click count:36
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Details

Product Name GPR102
Chinese Name G protein-coupled receptor102抗体
Alias G protein coupled receptor 102; G-protein coupled receptor 102; GPR102; TA5; TAAR8; TAAR8_HUMAN; TaR-5; TaR-8; TAR5; Trace amine assiciated receptor 8; Trace amine receptor 5; Trace amine receptor 8; Trace amine-associated receptor 8; TRAR5; GPCR GPR102.  
Research Area Neurobiology  Signal transduction  The cell membrane受体  G protein-coupled receptor  G protein signal  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 38kDa
Cellular localization The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human GPR102: 51-150/342 <Extracellular>
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Trace amines are endogenous molecules structurally related to classical biogenic amines that are linked to psychiatric conditions. A family of G-protein coupled receptors referred to as trace-amine-associated receptors (TAAR) are activated by trace amines and are present in very low levels in mammalian tissue. TaRs contain several structural features that are similar to the rhodopsin ∫-adrenergic receptor superfamily, including the positions of the seven transmembrane regions that provide common ligand-binding pockets as well as the short N- and C-terminal domains. TAAR proteins are potential targets for drugs of abuse, such as amphetamine and MDMA, as well as neuropsychiatric disorders including schizophrenia, depression, and attention deficit disorder.

Function:
Orphan receptor. Could be a receptor for trace amines. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Expressed in kidney and amygdala. Not expressed in other tissues or brain regions tested.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
Q969N4

Gene ID:
83551

Database links:

Entrez Gene: 83551 Human

Omim: 606927 Human

SwissProt: Q969N4 Human

Unigene: 350571 Human



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