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Product Name Phospho-Serine Chinese Name 磷酸化丝氨酸抗体 Alias Phosphoserine; phospho-Ser; phospho Ser; pan phospho Ser; pan-phospho Ser; pS; p-S; pSER; p-SER; p-serine; pan p-serine. 泛丝氨酸Phosphorylated anti; 泛丝氨酸磷酸化; 泛磷酸化丝氨酸; literatures Specific References (2) | SL11993R has been referenced in 2 publications.[IF=6.6] Jiajia Li. et al. Phosphorylation-Mediated Molecular Pathway Changes in Human Pituitary Neuroendocrine Tumors Identified by Quantitative Phosphoproteomics. Cells-Basel. 2021 Sep;10(9):2225 WB ; Human.[IF=3.88] Fu, Juanli, et al. "Tetrachlorobenzoquinone exerts neurological pro-inflammatory activity by promoting HMGB1 release, which induces TLR4 clustering within the lipid raft." Toxicological Sciences (2016): kfw124. WB ; Mouse.Product Type Phosphorylated anti Small molecule anti Research Area Tumour Neurobiology Signal transduction Kinases and Phosphatases The new supersedes the old Immunogen Species Rabbit Clonality Polyclonal React Species Human, (predicted: Rat, Chicken, Dog, Cow, Goose, Monkey, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated Phosphoserine Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Changes in the serine/threonine phosphorylation state of a protein in response to various external stimuli can have profound effects on cellular signal transduction, apoptosis and carcinogenesis. The reagents, including phosphorylated protein/peptides, antibodies against the phosphospecific amino acid, are important tools to explore the activation of serine, threonine or tyrosine containing proteins. An aberrant protein phosphorylation is a hallmark of human disease, and the enzymes, particularly protein kinases, which control protein phosphorylation are recognized as a major new drug target family.
SWISS:
N/A
CAS:
407-41-0
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