Product Name	GATAD1
Chinese Name	眼发育相关基因蛋白ODAG抗体
Alias	ODAG; GATA zinc finger domain containing 1; Ocular development associated gene; GATA zinc finger domain-containing protein 1; ocular development-associated gene protein; GATAD1 protein; ocular development associated; ODAG; RG083M05.2; tcag7.279; GATD1_HUMAN.
literatures	Specific References  (1)     |     SL11921R has been referenced in 1 publications. [IF=4.3] Ma, Xiaoling, et al. "Decreased expression and DNA methylation levels of GATAD1 in preeclamptic placentas." Cellular Signalling (2014).  IHC-P ;  Human.   PubMed:24462704
Research Area	Cell biology  Neurobiology  Signal transduction  Growth factors and hormones  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, )
Applications	ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	29kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human GATAD1/ODAG: 61-160/269
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The protein encoded by this gene contains a zinc finger at the N-terminus, and is thought to bind to a histone modification site that regulates gene expression. Mutations in this gene have been associated with autosomal recessive dilated cardiomyopathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012] Function: ODAG (Ocular development-associated gene), a novel transcription factor located on chromosome 7, encodes a protein that may play a role in eye development. mRNA profiling in multiple human tissue indicates that ODAG is expressed in human CD56+ NK cells and thyroid tissue. Subunit: Component of a chromatin complex, at least composed of KDM5A, GATAD1 and EMSY. Subcellular Location: Nuclear Tissue Specificity: Ubiquitously expressed among various tissue types. Expressed in left ventricular myocytes. DISEASE: Defects in GATAD1 are the cause of cardiomyopathy, dilated type 2B (CMD2B) [MIM:614672]. CMD2B is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death. Similarity: Contains 1 GATA-type zinc finger. SWISS: Q8WUU5 Gene ID: 57798 Database links: Entrez Gene: 57798 Human Entrez Gene: 67210 Mouse SwissProt: Q8N5Y5 Human SwissProt: Q8WUU5 Human SwissProt: Q3TS14 Mouse SwissProt: Q8VCQ2 Mouse SwissProt: Q920S3 Mouse SwissProt: Q9CSG2 Mouse Unigene: 21145 Human

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