Product Name	LBX1
Chinese Name	转录因子LBX1抗体
Alias	Homeobox; HPX 6; HPX6 antibodyLady bird like homeobox; Ladybird homeobox 1; Ladybird homeobox homolog 1; Ladybird homeobox protein homolog 1; LBX 1; LBX 1H; LBX1H; Transcription factor LBX1; Transcription factor similar to D. melanogaster homeodomain protein lady bird late; LBX1_HUMAN.
Research Area	Cell biology  Neurobiology  Signal transduction  Stem cells  transcriptional regulatory factor
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Zebrafish, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	30kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human LBX1: 166-250/281
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The human homolog of the Drosophila lady bird late gene, LBX1, is specifically expressed in the developing central nervous system and musculoskeletal system. The LBX1 gene has a restrictive expression pattern in the dorsal portion of the mantle of the spinal cord and the hindbrain of the CNS. In the developing mouse and chicken musculoskeletal system, Lbx1 is expressed in migrating limb muscle precursor cells. In addition, Lbx1 may regulate migratory patterns of limb muscle cell precursors and may be essential to dorsal identification of forelimb muscles. Function: This gene and the orthologous mouse gene were found by their homology to the Drosophila lady bird early and late homeobox genes. In the mouse, this gene is a key regulator of muscle precursor cell migration and is required for the acquisition of dorsal identities of forelimb muscles. Subunit: Interacts with SKOR1 which acts as a transcriptional corepressor Subcellular Location: Nuclear Similarity: Contains 1 homeobox DNA-binding domain. SWISS: P52954 Gene ID: 10660 Database links: Entrez Gene: 10660 Human Entrez Gene: 16814 Mouse Entrez Gene: 499362 Rat Omim: 604255 Human SwissProt: P52954 Human SwissProt: P52955 Mouse SwissProt: Q1XID0 Rat Unigene: 37128 Human

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