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Product Name SLC14A2 Chinese Name 尿素转运型glycoproteinA2抗体 Alias UT-A; HUT2; kidney; MGC119566; MGC119567; Slc14a2; Solute carrier family 14 (urea transporter), member 2; Solute carrier family 14 member 2; Urea transporter 2; Urea transporter; Urea transporter, kidney; UT-A2; UT2; UT2_HUMAN; UTA; UTR; FLJ16167; hUT-A6. literatures Specific References (1) | SL11801R has been referenced in 1 publications.[IF=2.976] Franziska Jäger. et al. Immunohistochemical detection of urea transporter-A in the tear-producing part of the lacrimal system. ANN ANAT. 2022 Oct;244:151991 IHC ; Human, Mouse, Pig.Research Area Tumour Neurobiology Signal transduction Channel protein The new supersedes the old Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, ) Applications WB=1:500-2000 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 101kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human SLC14A2/UT-A: 501-600/920 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The protein encoded by this gene belongs to the urea transporter family. In mammalian cells, urea is the chief end product of nitrogen catabolism, and plays an important role in the urinary concentration mechanism. This protein is expressed in the inner medulla of the kidney, and mediates rapid transepithelial urea transport across the inner medullary collecting duct. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2011]
Function:
Specialized low-affinity vasopressin-regulated urea transporter. Mediates rapid transepithelial urea transport across the inner medullary collecting duct and plays a major role in the urinary concentrating mechanism.
Subunit:
Isoform 1 interacts with SNAPIN which may be important for recruitment to the plasma membrane.
Subcellular Location:
Apical cell membrane; Multi-pass membrane protein.
Tissue Specificity:
Isoform 1 and isoform 2 are expressed in the inner medulla of the kidney.
Similarity:
Belongs to the urea transporter family.
SWISS:
Q15849
Gene ID:
8170
Database links:Entrez Gene: 8170 Human
Entrez Gene: 27411 Mouse
Omim: 601611 Human
SwissProt: Q15849 Human
SwissProt: Q8R4T9 Mouse
Unigene: 710927 Human
Unigene: 44158 Mouse
Unigene: 10157 Rat
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