Product Name	Calpain 14
Chinese Name	钙激活蛋白酶14抗体
Alias	Calcium-activated neutral proteinase 14; Calpain-14; CAN14_HUMAN; CANP 14; CAPN14.
Research Area	Cell biology  Neurobiology  Ubiquitin
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	80kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Calpain 14: 151-250/684
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Calpains are a family of cytosolic calcium-activated cysteine proteases involved in a variety of cellular processes including apoptosis, cell division, modulation of integrin-cytoskeletal interactions, and synaptic plasticity (Dear et al., 2000 [PubMed 10964513]). CAPN14 belongs to the calpain large subunit family. Function: Calcium-regulated non-lysosomal thiol-protease. Similarity: Belongs to the peptidase C2 family. Contains 1 calpain catalytic domain. Contains 3 EF-hand domains. SWISS: A8MX76 Gene ID: 440854 Database links: Entrez Gene: 440854 Human Omim: 610229 Human SwissProt: A8MX76 Human Unigene: 468059 Human

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