Product Name	Saitohin
Chinese Name	Saitohin蛋白抗体
Alias	MAPTIT; Saitohin; STH; STH_HUMAN.
Research Area	Cell biology  Neurobiology  Alzheimer's
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	14kDa
Cellular localization	The nucleus cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human STH/Saitohin: 51-128/128
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The intronless STH gene lies between exons 9 and 10 of the tau gene, which is implicated in a number of neurodegenerative disorders. It encodes a 128 residue protein with no clear homologs, and mimics the expresison patterns of tau. Though a polymorphism (Q7R) appears significant, data does not clearly show thus far whether or not this phenotype provides a useful marker for Alzheimer’s or other forms of neurodegenerative disease. Function: Highest expression in placenta, muscle, fetal brain, and adult brain, with lower expression in heart, kidney, stomach, testis, and adrenal gland. In the central nervous system, highest expression is in temporal lobe, hypothalamus, medulla and spinal cord, with lower expression in other brain regions. Subcellular Location: Cytoplasm. Nucleus. Tissue Specificity: Highest expression in placenta, muscle, fetal brain, and adult brain, with lower expression in heart, kidney, stomach, testis, and adrenal gland. In the central nervous system, highest expression is in temporal lobe, hypothalamus, medulla and spinal cord, with lower expression in other brain regions. SWISS: Q8IWL8 Gene ID: 246744 Database links: Entrez Gene: 246744 Human Omim: 607067 Human SwissProt: Q8IWL8 Human Unigene: 661831 Human

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