Product Name	LRRC10
Chinese Name	富含亮氨酸重复蛋白10抗体
Alias	HRLRRP; leucine-rich repeat-containing protein 10; Leucine-rich repeat-containing protein 10 Gene names; Leucine-rich repeat-containing protein 10 Gene names; LRRC10A; LRC10_HUMAN.
Research Area	Cardiovascular  immunology  Neurobiology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep, )
Applications	ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	32kDa
Cellular localization	The nucleus
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human LRRC10: 101-200/277
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic Alpha/Beta horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. The primary function of these motifs is to provide a versatile structural framework to mediate the formation of protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. LRRC10 (leucine-rich repeat-containing protein 10), also known as HRLRRP or LRRC10A, is a 277 amino acid protein that contains eight LRR repeats. Localized to the nucleus, LRRC10 may play an important role in cardiac development and/or cardiac function. The gene that encodes LRRC10 maps to human chromosome 12q15 and murine chromosome 10 D2. Function: May play important roles in cardiac development and/or cardiac function (By similarity). Subcellular Location: Nucleus Similarity: Contains 7 LRR (leucine-rich) repeats. SWISS: Q5BKY1 Gene ID: 376132 Database links: Entrez Gene: 376132 Human Entrez Gene: 237560 Mouse Omim: 610846 Human SwissProt: Q5BKY1 Human SwissProt: Q3UQT4 Mouse

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