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Product Name ALS2CR1 Chinese Name 肌萎缩侧索硬化症相关蛋白1抗体 Alias ALS2CR1; Amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 1; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 1 protein; CALS-7; MDS015; Ngg1 interacting factor 3-like 1; NIF3 (Ngg1 interacting factor 3, S.pombe homolog)-like 1; NIF3 NGG1 interacting factor 3-like 1 (S. pombe); NIF3 NGG1 interacting factor 3-like 1; NIF3-like protein 1; NIF3L_HUMAN; NIF3L1. Research Area Cell biology Neurobiology Alzheimer's Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Cow, Rabbit, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 42kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human ALS2CR1/NIF3L1: 201-300/377 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The NGG1 interacting factor 3-like 1 (NIF3L1) is a 377 amino acid protein expressed mainly in the cytoplasm of cells in several different tissues. It has been highly conserved throughout evolution, from bacteria to mammals. NIF3L participates in retinoic acid-primed neural differentiation of P19 embryonic carcinoma cells by cooperating with Trip15/CSN2, a transcriptional corepressor/component of COP9 signalosome. NIF3L1 interacts with itself and with the NIF3L1 binding protein 1 (NIF3L1 BP1), which is a novel protein presumed to contain a leucine zipper domain.
Subunit:
Homodimer. Interacts with COPS2. Interacts with THOC7.
Subcellular Location:
Cytoplasm.
Similarity:
Belongs to the UPF0135 (NIF3) family.
SWISS:
Q9GZT8
Gene ID:
60491
Database links:Entrez Gene: 60491 Human
Entrez Gene: 65102 Mouse
NCBI: 11141899 Human
Omim: 605778 Human
SwissProt: Q9GZT8 Human
SwissProt: Q9EQ80 Mouse
Unigene: 145284 Human
Unigene: 340248 Mouse
Unigene: 18112 Rat
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