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Product Name OR10A5 Chinese Name 味觉受体蛋白家族10亚基5抗体 Alias HP3; O10A5_HUMAN; Olfactory receptor 10A1; Olfactory receptor 10A5; Olfactory receptor 11-403; Olfactory receptor-like protein JCG6; OR10A1; OR10A5; OR11-403; R10A1. Research Area Cell biology Neurobiology Signal transduction The cell membrane受体 G protein-coupled receptor G protein signal Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 35kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human OR10A5: 231-317/317 <Extracellular> Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that leads to the perception of smell. While they share a seven transmembrane domain structure with many neurotransmitter and hormone receptors, olfactory receptors are responsible for the recognition and transduction of odorant signals. OR10A2 (olfactory receptor 10A2) and OR10A5 (olfactory receptor 10A5) are multi-pass membrane proteins that belong to the G-protein coupled receptor 1 family and are encoded by genes that map to human chromosome 11p15.4. Chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that map to chromosome 11.
Function:
Odorant receptor (Potential). May be involved in taste perception.
Subcellular Location:
Cell membrane; Multi-pass membrane protein.
Tissue Specificity:
Expressed in the tongue.
Similarity:
Belongs to the G-protein coupled receptor 1 family.
SWISS:
Q9H207
Gene ID:
144124
Database links:Entrez Gene: 144124 Human
SwissProt: Q9H207 Human
Unigene: 447478 Human
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