TEL: +86 571 56623320 EMAIL: [email protected]
Product Name HS1BP3 Chinese Name 造血Stem cells特异性相关Binding protein3抗体 Alias ETM2; FLJ14249; H1BP3_HUMAN; HCLS1 binding protein 3; HCLS1-binding protein 3; HS1 binding protein 3; HS1 BP3; HS1-BP3; HS1-binding protein 3; Hs1bp3; HSP1BP-3. Research Area Cell biology Neurobiology Signal transduction Stem cells Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) Applications ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 43kDa Cellular localization cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human HS1BP3: 51-130/392 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail HS1BP3 is a 392 amino acid protein that contains one PX (phox homology) domain, a leucine zipper, immunoreceptor tyrosine-based inhibitory motif-like motifs and multiple proline-rich regions. Expressed primarily in brain, HS1BP3 is encoded by a gene mapping to human chromosome 2p24.1. The gene encoding HS1BP3 is frequently mutated in familial essential tremor, a disorder characterized by kinetic tremor the the hands, voice or head, though there is no correlation to Parkinson disease. HS1BP3 interacts with HAX-1’s SH3 domain, and may also play a role in the regulation of catecholamine and serotonin metabolism. Acting as a regulator of IL-2 signaling, HS1BP3 is likely involved in lymphocyte activation.
Function:
May be a modulator of IL-2 signaling.
Subunit:
Binds HCLS1. Interacts with the SH3 domain of HCLS1 in vitro
Similarity:
Contains 1 PX (phox homology) domain.
SWISS:
Q53T59
Gene ID:
64342
Database links:Entrez Gene: 64342 Human
Entrez Gene: 100338217 Rabbit
Omim: 609359 Human
SwissProt: Q53T59 Human
Unigene: 531785 Human
Scan Wechat Qrcode