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Rabbit Anti-QRFP antibody
Rabbit Anti-QRFP antibody
26RFa; Neuropeptide RF-amide; OX26_HUMAN; pyroglutamylated RFamide peptide; P518; Pyroglutamylated arginine-phenylalanine-amide peptide; QRF-amide; Qrfp.
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  • NO.:SL11534R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Mouse,Rat,(predicted: Human,Pig,Cow,Horse,Sheep,)
    Applications:WB ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Product Name QRFP
Chinese Name 神经内分泌肽QRFP抗体
Alias 26RFa; Neuropeptide RF-amide; OX26_HUMAN; pyroglutamylated RFamide peptide; P518; Pyroglutamylated arginine-phenylalanine-amide peptide; QRF-amide; Qrfp.  
Research Area Cardiovascular  Cell biology  Neurobiology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Mouse, Rat,  (predicted: Human, Pig, Cow, Horse, Sheep, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 5kDa
Cellular localization Secretory protein 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human QRFP: 91-133/136 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail QRFP is a 136 amino acid secreted protein that is widely expressed in the brain with highest expression levels in the cerebellum, medulla, pituitary, retina, vestibular nucleus and white matter. Also expressed in the bladder, colon, coronary artery, parathyroid gland, prostate, testis and thyroid, QRFP is a member of the RFamide neuropeptide family. QRFP may be involved in aldosterone secretion by the adrenal gland and is also implicated in stimulating metabolic rate, locomotor activity and increasing blood pressure. Considered a ligand for the G-protein coupled receptor GPR103, QRFP may have orexigenic activity, thereby acting as an appetite stimulant. The gene encoding QFRP is located on human chromosome 9, which consists of about 145 million bases, comprises roughly 4% of the human genome and encodes nearly 900 genes.

Function:
Stimulates feeding behavior, metabolic rate and locomotor activity and increases blood pressure. May have orexigenic activity. May promote aldosterone secretion by the adrenal gland.

Subunit:
Ligand for the G-protein coupled receptor QRFPR/GPR103

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed widely in the brain with highest expression levels in the cerebellum, medulla, pituitary, retina, vestibular nucleus, and white matter. Also expressed in the bladder, colon, coronary artery, parathyroid gland, prostate, testis, and thyroid.

Similarity:
Belongs to the RFamide neuropeptide family.

SWISS:
P83859

Gene ID:
347148

Database links:

Entrez Gene: 347148 Human

Omim: 609795 Human

SwissProt: P83859 Human

Unigene: 660704 Human



Product Picture
Sample:
Lane 1: Mouse Cerebrum tissue lysates
Lane 2: Rat Cerebrum tissue lysates
Primary: Anti-QRFP (SL11534R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 5 kDa
Observed band size: 18 kDa

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