TEL: +86 571 56623320 EMAIL: [email protected]
Product Name Sperm Flagellar 2 Chinese Name 精子鞭毛蛋白2抗体 Alias KPL2; MGC102842; Protein KPL2; SPEF2; sperm flagellar protein 2; FLJ23164; FLJ23577; FLJ25395; KIAA1770; SPEF2_HUMAN; CT122. literatures Specific References (1) | SL11488R has been referenced in 1 publications.[IF=7.129] Xing Guo. et al. Microcystin leucine arginine induces human sperm damage: Involvement of the Ca2+/CaMKKβ/AMPK pathway. ECOTOX ENVIRON SAFE. 2023 May;256:114845 IF ; Human.Research Area Cell biology Developmental biology Neurobiology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, ) Applications ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 210kDa Cellular localization The nucleus cytoplasmic Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human KPL2/Sperm Flagellar 2: 227-275/1822 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Flagella and cillia are both membrane-bound projections from the cell surface that beat in distinctive patterns. Cilia are shorter and usually more profuse than flagella and contain a microtubule cytoskeleton, the ciliary axoneme, surrounded by a ciliary membrane. The ciliary membranes of all cilia hold specific receptors and ion channel proteins that initiate signaling pathways that regulate motility and/or link mechanical or chemical stimuli to intracellular transduction cascades regulating differentiation, migration and cell growth during development and in adulthood. KPL2, also known as SPEF2 (sperm flagellar 2), is a 1,822 amino acid protein that contains a calponin homology domain, three nuclear localization signals, a consensus P-loop and a proline-rich region. Required for correct axoneme develoment, KPL2 is predominantly expressed in cells with cilia or flagella. Four isoforms of KPL2 exists as a result of alternative splicing events.
Function:
Required for correct axoneme develoment
Similarity:
Contains 1 CH (calponin-homology) domain.
SWISS:
Q9C093
Gene ID:
79925
Database links:Entrez Gene: 79925 Human
SwissProt: Q9C093 Human
Scan Wechat Qrcode