Product Name	TXNDC11
Chinese Name	硫氧还蛋白11抗体
Alias	EF-hand-binding protein 1; EFP1; RGD1307538; Thioredoxin domain-containing protein 11; TXD11_HUMAN; TXNDC11; 2810408E11Rik; AI427833.
Research Area	Tumour  Cell biology  Signal transduction  transcriptional regulatory factor
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Cow, Horse, Sheep, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	110kDa
Cellular localization	cytoplasmic The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human TXNDC11: 601-700/985
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation. Function: May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation. Subunit: Interacts with the cytoplasmic part of DUOX1 and DUOX2. Interacts with TPO and CYBA. Subcellular Location: Endoplasmic reticulum membrane. Tissue Specificity: Widely expressed at low level. Expressed at higher level in thyroid and prostate. Similarity: Belongs to the protein disulfide isomerase family. Contains 2 thioredoxin domains. SWISS: Q6PKC3 Gene ID: 51061 Database links: Entrez Gene: 490003 Dog Entrez Gene: 100056118 Horse Entrez Gene: 51061 Human SwissProt: Q6PKC3 Human Unigene: 313847 Human

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