TEL: +86 571 56623320 EMAIL: [email protected]
Product Name Adrenodoxin Chinese Name 肾上腺皮质Mitochondrion铁氧还蛋白抗体 Alias Adrenal ferredoxin; Adrenodoxin; Adrenodoxin, mitochondrial; ADX; ADX_HUMAN; FDX; fdx1; Ferredoxin 1; Ferredoxin-1; Hepatoredoxin; LOH11CR1D; Mitochondrial adrenodoxin; mitochondrial. literatures Specific References (1) | SL11426R has been referenced in 1 publications.[IF=8.786] Jiateng Hu. et al. Identification of core cuprotosis-correlated biomarkers in abdominal aortic aneurysm immune microenvironment based on bioinformatics. FRONT IMMUNOL. 2023; 14: 1138126 IF ; Mouse.Research Area Tumour Cell biology Neurobiology Signal transduction Growth factors and hormones Mitochondrion Immunogen Species Rabbit Clonality Polyclonal React Species Rat, (predicted: Human, Mouse, Sheep, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 13.5kDa Cellular localization cytoplasmic Mitochondrion Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human Adrenodoxin/FDX: 51-150/184 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a small iron-sulfur protein that transfers electrons from NADPH through ferredoxin reductase to mitochondrial cytochrome P450, involved in steroid, vitamin D, and bile acid metabolism. Pseudogenes of this functional gene are found on chromosomes 20 and 21. [provided by RefSeq, Aug 2011]
Function:
Participates in the synthesis of thyroid hormones. Transfers electrons from adrenodoxin reductase to the cholesterol side chain cleavage cytochrome P450.
Subcellular Location:
Mitochondrion matrix.
Tissue Specificity:
Highest levels in the adrenal gland (at protein level). Also detected in kidney and testis (at protein level).
Similarity:
Belongs to the adrenodoxin/putidaredoxin family.
Contains 1 2Fe-2S ferredoxin-type domain.
SWISS:
P10109
Gene ID:
2230
Database links:Entrez Gene: 2230 Human
Entrez Gene: 14148 Mouse
Omim: 103260 Human
SwissProt: P10109 Human
SwissProt: P46656 Mouse
Unigene: 744 Human
Unigene: 1061 Mouse
Unigene: 440190 Mouse
Unigene: 6946 Rat
Product Picture Paraformaldehyde-fixed, paraffin embedded (rat adrenal gland tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Adrenodoxin) Polyclonal Antibody, Unconjugated (SL11426R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Scan Wechat Qrcode