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Rabbit Anti-Adrenodoxin antibody
Rabbit Anti-Adrenodoxin antibody
Adrenal ferredoxin; Adrenodoxin; Adrenodoxin, mitochondrial; ADX; ADX_HUMAN; FDX; fdx1; Ferredoxin 1; Ferredoxin-1; Hepatoredoxin; LOH11CR1D; Mitochondrial adrenodoxin; mitochondrial.
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  • NO.:SL11426R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Rat,(predicted: Human,Mouse,Sheep,)
    Applications:WB ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Details

Product Name Adrenodoxin
Chinese Name 肾上腺皮质Mitochondrion铁氧还蛋白抗体
Alias Adrenal ferredoxin; Adrenodoxin; Adrenodoxin, mitochondrial; ADX; ADX_HUMAN; FDX; fdx1; Ferredoxin 1; Ferredoxin-1; Hepatoredoxin; LOH11CR1D; Mitochondrial adrenodoxin; mitochondrial.  
literatures
Specific References  (1)     |     SL11426R has been referenced in 1 publications.
[IF=8.786] Jiateng Hu. et al. Identification of core cuprotosis-correlated biomarkers in abdominal aortic aneurysm immune microenvironment based on bioinformatics. FRONT IMMUNOL. 2023; 14: 1138126  IF ;  Mouse.  
Research Area Tumour  Cell biology  Neurobiology  Signal transduction  Growth factors and hormones  Mitochondrion  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Rat,  (predicted: Human, Mouse, Sheep, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 13.5kDa
Cellular localization cytoplasmic Mitochondrion
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human Adrenodoxin/FDX: 51-150/184 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail This gene encodes a small iron-sulfur protein that transfers electrons from NADPH through ferredoxin reductase to mitochondrial cytochrome P450, involved in steroid, vitamin D, and bile acid metabolism. Pseudogenes of this functional gene are found on chromosomes 20 and 21. [provided by RefSeq, Aug 2011]

Function:
Participates in the synthesis of thyroid hormones. Transfers electrons from adrenodoxin reductase to the cholesterol side chain cleavage cytochrome P450.

Subcellular Location:
Mitochondrion matrix.

Tissue Specificity:
Highest levels in the adrenal gland (at protein level). Also detected in kidney and testis (at protein level).

Similarity:
Belongs to the adrenodoxin/putidaredoxin family.
Contains 1 2Fe-2S ferredoxin-type domain.

SWISS:
P10109

Gene ID:
2230

Database links:

Entrez Gene: 2230 Human

Entrez Gene: 14148 Mouse

Entrez Gene: 29189 Rat

Omim: 103260 Human

SwissProt: P10109 Human

SwissProt: P46656 Mouse

SwissProt: P24483 Rat

Unigene: 744 Human

Unigene: 1061 Mouse

Unigene: 440190 Mouse

Unigene: 6946 Rat



Product Picture
Paraformaldehyde-fixed, paraffin embedded (rat adrenal gland tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Adrenodoxin) Polyclonal Antibody, Unconjugated (SL11426R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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