Product Name	Synaptotagmin-2
Chinese Name	突触Binding protein相关基因2抗体
Alias	Synaptotagmin 2; Synaptotagmin II; Synaptotagmin2; SynaptotagminII; SYT 2; Syt II; SytII.Synaptotagmin II; SYNII; Syt2; RATSYNII; SYNII; FLJ42519; KIAA4194; LOC100127887; mKIAA4194; R74640; RATSYNII; SYNAPTOTAGMIN 2; SYT2; SytII; SYT2_HUMAN.
literatures	Specific References  (1)     |     SL1136R has been referenced in 1 publications. [IF=4.5] Shaoping Zhong. et al. GABAergic Interneuron and Neurotransmission Are mTOR-Dependently Disturbed in Experimental Focal Cortical Dysplasia. Mol Neurobiol. 2021 Jan;58(1):156-169  IHC ;  Mouse.   PubMed:32909150
Research Area	Cell biology  Neurobiology  Binding protein
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	46kDa
Cellular localization	cytoplasmic The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human synaptotagmin-2: 285-380/419
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Synaptotagmins, like SYT2, are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (Hilbush and Morgan, 1994 [PubMed 8058779]).[supplied by OMIM] Subunit: Homotetramer. Interacts with stonin 2. Interacts with SCAMP5. Subcellular Location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane; Single-pass membrane protein. Similarity: Belongs to the synaptotagmin family. Contains 2 C2 domains. SWISS: Q8N9I0 Gene ID: 127833 Database links: Entrez Gene: 127833 Human Entrez Gene: 20980 Mouse Entrez Gene: 24805 Rat Omim: 600104 Human SwissProt: Q8N9I0 Human SwissProt: P46097 Mouse SwissProt: P29101 Rat Unigene: 25422 Human Unigene: 5102 Mouse Unigene: 88574 Rat

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