Product Name	PTP zeta
Chinese Name	磷酸蛋白聚糖PTPRZ抗体
Alias	Phosphacan; 3F8 chondroitin sulfate proteoglycan; 3H1 keratan sulfate proteoglycan; HPTPZ; HPTPzeta; protein tyrosine phosphatase receptor type Z1; Protein tyrosine phosphatase receptor type Z polypeptide 2; Protein tyrosine phosphatase, receptor type, Z polypeptide 1; Protein tyrosine phosphatase, receptor type, zeta polypeptide 1; PTP-ZETA; PTP18; PTPRZ; PTPRZ1; PTPZ; R PTP zeta 2; R-PTP-zeta; Receptor type tyrosine phosphatase beta/zeta; Receptor-type tyrosine-protein phosphatase zeta; RPTP-BETA; RPTPB; RPTPbeta; PTPRZ_HUMAN; PTPζ.
Research Area	Cell biology  Neurobiology  Signal transduction  Kinases and Phosphatases
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Mouse,  (predicted: Rat, )
Applications	ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	251kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human PTP zeta: 421-520/2315 <Extracellular>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes a member of the receptor protein tyrosine phosphatase family. Expression of this gene is restricted to the central nervous system (CNS), and it may be involved in the regulation of specific developmental processes in the CNS. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011] Function: May be involved in the regulation of specific developmental processes in the CNS. Subunit: The carbonic-anhydrase like domain binds to contactin (By similarity). Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Specifically expressed in the central nervous system, where it is localized in the Purkinje cell layer of the cerebellum, the dentate gyrus, and the subependymal layer of the anterior horn of the lateral ventricle. Developmentally regulated in the brain. Similarity: Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily. Contains 1 alpha-carbonic anhydrase domain. Contains 1 fibronectin type-III domain. Contains 2 tyrosine-protein phosphatase domains. SWISS: P23471 Gene ID: 5803 Database links: Entrez Gene: 5803 Human Entrez Gene: 19283 Mouse Entrez Gene: 25613 Rat Omim: 176891 Human SwissProt: P23471 Human SwissProt: Q62656 Rat Unigene: 489824 Human Unigene: 10088 Rat

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