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Rabbit Anti-STX6 antibody
Rabbit Anti-STX6 antibody
STX 6; STX-6; STX6_HUMAN; Syntaxin-6; Syntaxin 6; Syntaxin6.
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  • NO.:SL11261R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Rabbit,Sheep,)
    Applications:ELISA
    concentration:1mg/ml
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Details

Product Name STX6
Chinese Name 突触融合蛋白6抗体
Alias STX 6; STX-6; STX6_HUMAN; Syntaxin-6; Syntaxin 6; Syntaxin6.  
Research Area Cell biology  Neurobiology  Signal transduction  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep, )
Applications ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 29kDa
Cellular localization cytoplasmic The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human STX6: 161-255/255 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Enables syntaxin binding activity. Involved in several processes, including Golgi ribbon formation; retrograde transport, endosome to Golgi; and vesicle fusion. Acts upstream of or within endocytic recycling. Located in several cellular components, including early endosome; perinuclear region of cytoplasm; and trans-Golgi network. Part of SNARE complex. [provided by Alliance of Genome Resources, Apr 2022]

Function:
Involved in intracellular vesicle trafficking.

Subunit:
Binds EEA1. Interacts with VPS45A. Interacts with MARCH2 and MARCH3 (By similarity). Interacts with GOPC. Identified in a complex containing STX6, STX12, VAMP4 and VTI1A.

Subcellular Location:
Golgi apparatus membrane.

Similarity:
Belongs to the syntaxin family. Contains 1 t-SNARE coiled-coil homology domain.

SWISS:
O43752

Gene ID:
10228

Database links:

Entrez Gene: 10228 Human

Entrez Gene: 58244 Mouse

Entrez Gene: 60562 Rat

Omim: 603944 Human

SwissProt: O43752 Human

SwissProt: Q9JKK1 Mouse

SwissProt: Q63635 Rat



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