Product Name	NXPH2
Chinese Name	神经外营养蛋白2抗体
Alias	Neurexophilin2; Neurexophilin 2; Neurexophilin-2; NPH2; Nxph2; Nxph-2; NXPH2_HUMAN; MGC125479; MGC125477; MGC125478; MGC125480.
Research Area	Neurobiology  Signal transduction  Cell adhesion molecule
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	27kDa
Cellular localization	Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human NXPH2: 151-250/264
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Neurexophilin family (Neurexophilin-1-4) of neuropeptide-like glycoproteins that are proteolytically processed after synthesis. Neurexophilin-1-3 are secreted proteins that are thought to function as signaling molecules which specifically bind to target proteins, such as neurexin I?(a protein that promotes adhesion between dendrites and axons), and are essential for proper neurotransmitter release. While Neurexophilin-1 is located primarily in spleen tissue, Neurexophilin-2 is expressed primarily in kidney and both Neurexophilin-2 and Neurexophilin-3 are highly expressed in brain. Defects in the gene encoding Neurexophilin-1 may be associated with schizophrenia, a mental disorder characterized by an abnormal perception of reality. Function: May be signaling molecules that resemble neuropeptides and that act by binding to alpha-neurexins and possibly other receptors. Subunit: Belongs to the neurexophilin family. Subcellular Location: Secreted. Tissue Specificity: Expressed in brain and kidney. Post-translational modifications: May be proteolytically processed at the boundary between the N-terminal non-conserved and the central conserved domain in neuron-like cells (By similarity). Similarity: Belongs to the neurexophilin family. SWISS: O95156 Gene ID: 11249 Database links: Entrez Gene: 11249 Human Entrez Gene: 18232 Mouse Entrez Gene: 679932 Rat Omim: 604635 Human SwissProt: O95156 Human SwissProt: Q61199 Mouse

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