TEL: +86 571 56623320 EMAIL: [email protected]
Product Name PCDHGA2 Chinese Name 原钙粘蛋白γA2抗体 Alias PCDHG-A2; PCDH gamma A2; Protocadherin gamma A2; Protocadherin gamma subfamily A 2; PCDG2_HUMAN. Research Area Signal transduction Cell adhesion molecule Cytoskeleton The cell membrane蛋白 Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Rat, ) Applications WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 98kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human PCDHGA2: 61-160/932 <Extracellular> Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHGA2 (Protocadherin gamma A2) is a 932 amino acid protein that is one of 22 proteins encoded by the protocadherin gamma cluster. The protocadherein gamma cluster consists of three subfamilies (A, B and C) and PCDHGA2 is a member of the gamma subfamily A. PCDHGA2 contains six cadherin motifs, and characteristic of gamma protocadherins, PCDHGA2 is a type I transmembrane receptor expressed in the central nervous system and localizes to synapses. Members of the gamma cluster of protocadherins are essential for neuronal survival.
Function:
Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.
Subcellular Location:
Cell membrane; Single-pass type I membrane protein.
Similarity:
Contains 6 cadherin domains.
SWISS:
Q9Y5H1
Gene ID:
56113
Database links:Entrez Gene: 56113 Human
Entrez Gene: 93710 Mouse
UniProtKB/Swiss-Prot: Q9Y5H1.1
Product Picture
Scan Wechat Qrcode