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Rabbit Anti-ROM1 antibody
Rabbit Anti-ROM1 antibody
Retinal outer segment membrane protein 1; Rod outer segment membrane protein 1; ROM; ROM1; ROM1_HUMAN; ROSP1; RP7; Tetraspanin 23; Tetraspanin-23; Tspan 23; Tspan-23; TSPAN23.
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  • NO.:SL11125R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep,Cat,)
    Applications:WB ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Details

Product Name ROM1
Chinese Name 视网膜感光细胞外节膜蛋白1抗体
Alias Retinal outer segment membrane protein 1; Rod outer segment membrane protein 1; ROM; ROM1; ROM1_HUMAN; ROSP1; RP7; Tetraspanin 23; Tetraspanin-23; Tspan 23; Tspan-23; TSPAN23.  
Research Area Neurobiology  Cell adhesion molecule  The cell membrane蛋白  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Cat, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 37kDa
Cellular localization The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human ROM1: 121-220/351 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail This gene is a member of a photoreceptor-specific gene family and encodes an integral membrane protein found in the photoreceptor disk rim of the eye. This protein can form homodimers or can heterodimerize with another photoreceptor, retinal degeneration slow (RDS). It is essential for disk morphogenesis, and may also function as an adhesion molecule involved in the stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. Certain defects in this gene have been associated with the degenerative eye disease retinitis pigmentosa. [provided by RefSeq, Jul 2008].

Function:
May function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. It is essential for disk morphogenesis.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Retina (photoreceptor). In rim region of ROS (rod outer segment) disks.

DISEASE:
Defects in ROM1 may cause retinitis pigmentosa (RP); when associated with defects in PRPH2.

Similarity:
Belongs to the PRPH2/ROM1 family.

SWISS:
Q03395

Gene ID:
6094

Database links:

Entrez Gene: 6094 Human

Entrez Gene: 19881 Mouse

Entrez Gene: 309201 Rat

Omim: 180721 Human

SwissProt: Q03395 Human

SwissProt: P32958 Mouse

SwissProt: Q5PPM7 Rat

Unigene: 281564 Human



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