Product Name	Neprilysin 2
Chinese Name	脑啡肽酶2抗体
Alias	Neprilysin-like Protease beta; Mel transforming oncogene like 1; Membrane metallo endopeptidase like 1; Membrane metallo endopeptidase like 2; MMEL1; Neprilysin2; Neprilysin-2; Neprilysin Like 1; MMEL2; NEPII; NL1; NL2; SEP; Soluble secreted endopeptidase.
Research Area	Neurobiology  Cell adhesion molecule  The cell membrane蛋白
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, )
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	89kDa
Cellular localization	The cell membrane Secretory protein
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Neprilysin 2: 451-550/779
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The protein encoded by this gene is a member of the neutral endopeptidase (NEP) or membrane metallo-endopeptidase (MME) family. Family members play important roles in pain perception, arterial pressure regulation, phosphate metabolism and homeostasis. This protein is a type II transmembrane protein and is thought to be expressed as a secreted protein. This gene is expressed mainly in testis with weak expression in the brain, kidney, and heart. [provided by RefSeq, Jul 2008]. Function: Metalloprotease involved in sperm function, possibly by modulating the processes of fertilization and early embryonic development. Degrades a broad variety of small peptides with a preference for peptides shorter than 3 kDa containing neutral bulky aliphatic or aromatic amino acid residues. Shares the same substrate specificity with MME and cleaves peptides at the same amide bond Subcellular Location: Membrane; Single pass type II membrane protein. Secreted. Tissue Specificity: Predominantly expressed in testis. Weakly expressed in brain, kidney and heart. Post-translational modifications: N-glycosylated Similarity: Belongs to the peptidase M13 family. SWISS: Q495T6 Gene ID: 79258 Database links: Entrez Gene: 79258 Human Entrez Gene: 27390 Mouse Entrez Gene: 313755 Rat SwissProt: Q495T6 Human SwissProt: Q9ERK3 Mouse SwissProt: P0C1T0 Rat Unigene: 591453 Human

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