Product Name	DNAH7
Chinese Name	轴丝动力蛋白7抗体
Alias	axonemal; Axonemal beta dynein heavy chain 7; Ciliary dynein heavy chain 7; DNAH7; DYH7_HUMAN; Dynein axonemal heavy chain 7; Dynein heavy chain 7; Dynein heavy chain-like protein 2; HDHC2; KIAA0944.
literatures	Specific References  (1)     |     SL11023R has been referenced in 1 publications. [IF=9.685] Wu, Huan. et al. DNALI1 deficiency causes male infertility with severe asthenozoospermia in humans and mice by disrupting the assembly of the flagellar inner dynein arms and fibrous sheath. CELL DEATH DIS. 2023 Feb;14(2):1-13  IF ;  Mouse,Human.   PubMed:36792588
Research Area	Neurobiology  Signal transduction  Cell adhesion molecule  Extracellular matrix
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	461kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human DNAH7: 2301-2400/4024
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	DNAH7 is a component of the inner dynein arm of ciliary axonemes (Zhang et al., 2002 [PubMed 11877439]).[supplied by OMIM, Mar 2008] Function: Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Subunit: The dynein complex consists of at least two heavy chains and a number of intermediate and light chains (By similarity). Subcellular Location: Cytoplasm; cytoskeleton; cilium axoneme. Tissue Specificity: Detected in brain, testis and trachea. Detected in bronchial cells (at protein level). Similarity: Belongs to the dynein heavy chain family. SWISS: Q8WXX0 Gene ID: 56171 Database links: Entrez Gene: 56171 Human Omim: 610061 Human SwissProt: Q8WXX0 Human Unigene: 97403 Human

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