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Product Name FOXP4 Chinese Name 叉头蛋白P4抗体 Alias 1200010K03Rik; 2310007G05Rik; FKHLA; FLJ40908; FLJ44184; Fork head related protein like A; Fork head-related protein-like A; Forkhead box P4; Forkhead box protein P4; FOX P4; FOXP 4; foxp4; FOXP4_HUMAN; hFKHLA; mFKHLA; OTTHUMP00000016374; OTTHUMP00000039784; OTTHUMP00000043412; OTTHUMP00000043536; Winged helix repressor FOX P4; Winged helix repressor FOXP 4; Winged helix repressor FOXP4. Research Area Tumour Cell biology transcriptional regulatory factor Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species Rat, (predicted: Human, Mouse, Chicken, Dog, Cow, Horse, Rabbit, Sheep, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 73kDa Cellular localization The nucleus Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human FOXP4: 1-100/680 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Many members of the forkhead box gene family, including members of subfamily P, have roles in mammalian oncogenesis. This gene may play a role in the development of tumors of the kidney and larynx. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. [provided by RefSeq, Jul 2008]
Function:
Transcriptional repressor that represses lung-specific expression.
Post-translational modifications:
Nucleus.
Similarity:
Contains 1 C2H2-type zinc finger.
Contains 1 fork-head DNA-binding domain.
SWISS:
Q8IVH2
Gene ID:
116113
Database links:Entrez Gene: 116113 Human
Entrez Gene: 74123 Mouse
Omim: 608924 Human
SwissProt: Q5W098 Human
SwissProt: Q8IVH2 Human
SwissProt: Q80V92 Mouse
SwissProt: Q8CG10 Mouse
SwissProt: Q8CIS1 Mouse
SwissProt: Q9DBY0 Mouse
Unigene: 131436 Human
Unigene: 240062 Mouse
Unigene: 64329 Rat
Product Picture Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (FOXP4) Polyclonal Antibody, Unconjugated (SL10990R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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