Product Name	SCGN
Chinese Name	促泌素抗体
Alias	SEGN_HUMAN; Secretagogin; SECRET; secretagogin, EF-hand calcium binding protein; SEGN; CALBL; setagin; DJ501N12.8;
Research Area	Cell biology  Neurobiology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Rat, Pig, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	32kDa
Cellular localization	cytoplasmic The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human SCGN: 151-250/276
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The encoded protein is a secreted calcium-binding protein which is found in the cytoplasm. It is related to calbindin D-28K and calretinin. This protein is thought to be involved in KCL-stimulated calcium flux and cell proliferation. [provided by RefSeq, Jul 2008] Subcellular Location: Cytoplasm. Secreted.Cytoplasmic vesicle, secretory vesicle membrane; Peripheralmembrane protein; Cytoplasmic side.Note=Predominantly cytoplasmic. A small proportion is associatedwith secretory granules and membrane fractions.Detectable in human serum after ischemic neuronal damage. Tissue Specificity: Expressed at high levels in the pancreatic islets of Langerhans and to a much lesser extent in the gastrointestinal tract (stomach, small intestine and colon), the adrenal medulla and cortex and the thyroid C-cells. In the brain, the expression is restricted to distinct subtypes of neurons with highest expression in the molecular layer of the cerebellum (stellate and basket cells), in the anterior part of the pituitary gland, in the thalamus, in the hypothalamus and in a subgroup of neocortical neurons. Similarity: Contains 6 EF-hand domains. SWISS: O76038 Gene ID: 10590 Database links: Entrez Gene: 10590 Human Entrez Gene: 306942 Rat SwissProt: O76038 Human SwissProt: Q6R556 Rat
Product Picture	Sample: Pancreas (Mouse) Lysate at 40 ug Primary: Anti- SCGN (SL10972R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 32 kD Observed band size: 32 kD

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