Product Name	Aquaporin 5
Chinese Name	水Channel protein5抗体
Alias	Aquaporin 5; AQP5; AQP 5; AQP-5; AQP5_HUMAN; Aquaporin-5.
literatures	Specific References  (2)     |     SL10927R has been referenced in 2 publications. [IF=3.266] Dai TQ et al. In vitro transdifferentiation of adipose tissue-derived stem cells into salivary gland acinar-like cells. Am J Transl Res. 2019 May 15;11(5):2908-2924.  ICF&WB ;  Mouse.   PubMed:31217863 [IF=2.027] Ba F et al. Lipoxin A4 ameliorates alveolar fluid clearance disturbance in lipopolysaccharide-induced lung injury via aquaporin 5 and MAPK signaling pathway. J Thorac Dis 2019;11(8):3599-3608  WB ;  Mouse.   PubMed:DOI:10.21037/jtd.2019.08.86
Research Area	Signal transduction  Channel protein
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Mouse,  (predicted: Rat, Pig, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	29kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Aquaporin 5: 151-250/265 <Extracellular>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Aquaporin 5 (AQP5) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions. AQP0, AQP2, AQP5, and AQP6 are closely related and all map to 12q13. [provided by RefSeq, Jul 2008] Function: Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions. Subcellular Location: Membrane; Multi-pass membrane protein. Similarity: Belongs to the MIP/aquaporin (TC 1.A.8) family. SWISS: P55064 Gene ID: 362 Database links: Entrez Gene: 362 Human Entrez Gene: 11830 Mouse Entrez Gene: 25241 Rat Omim: 600442 Human SwissProt: P55064 Human SwissProt: Q9WTY4 Mouse SwissProt: P47864 Rat Unigene: 298023 Human Unigene: 45580 Mouse Unigene: 10066 Rat
Product Picture	Sample: Eye (Rat) Lysate at 40 ug Primary: Anti-Aquaporin 5 (SL10927R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 29 kD Observed band size: 29 kD Tissue/cell: human laryngocarcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-Aquaporin Polyclonal Antibody, Unconjugated(SL10927R) 1:500, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

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