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Rabbit Anti-RBMY1A1 antibody
Rabbit Anti-RBMY1A1 antibody
hRBMY; MGC181956; RBM1; RBM2; RBMY; RNA binding motif protein 1; RNA binding motif protein 2; RNA binding motif protein Y chromosome family 1 member A1; RNA binding motif protein Y chromosome family 1 member A1/C; RNA binding motif protein Y chromosome fa
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  • NO.:SL10923R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,)
    Applications:ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Product Name RBMY1A1
Chinese Name RNABinding protein片段Y染色体家族蛋白1抗体
Alias hRBMY; MGC181956; RBM1; RBM2; RBMY; RNA binding motif protein 1; RNA binding motif protein 2; RNA binding motif protein Y chromosome family 1 member A1; RNA binding motif protein Y chromosome family 1 member A1/C; RNA binding motif protein Y chromosome family 1 member; RNA binding motif protein Y linked family 1 member A1; Y chromosome RNA recognition motif 1; YRRM1; YRRM2; RBY1A_HUMAN.  
Research Area Developmental biology  Stem cells  Binding protein  Epigenetics  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, )
Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 56kDa
Cellular localization The nucleus 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human RBMY1A1: 81-180/496 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail This gene encodes a protein containing an RNA-binding motif in the N-terminus and four SRGY (serine, arginine, glycine, tyrosine) boxes in the C-terminus. Multiple copies of this gene are found in the AZFb azoospermia factor region of chromosome Y and the encoded protein is thought to be involved in spermatogenesis. Most copies of this locus are pseudogenes, although six highly similar copies have full-length ORFs and are considered functional. Four functional copies of this gene are found within inverted repeat IR2; two functional copies of this gene are found in palindrome P3, along with two copies of PTPN13-like, Y-linked. [provided by RefSeq, Jul 2008]

Function:
RBMY1A1 is an RNA-binding protein which may be involved in spermatogenesis. It is required for sperm development, possibly by participating in pre-mRNA splicing in the testis.

Subunit:
Interacts with splicing factor proteins SFRS3/SRP20, TRA2B/SFRS10, KHDRBS1/SAM68 and KHDRBS3.

Subcellular Location:
Nuclear.

Tissue Specificity:
Testis-specific.

Similarity:
Contains 1 RRM (RNA recognition motif) domain.

SWISS:
P0DJD3

Gene ID:
5940

Database links:

Entrez Gene: 5940 Human

Omim: 400006 Human

SwissProt: P0DJD3 Human

Unigene: 380450 Human



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