Product Name	FMDV VP1
Chinese Name	口蹄疫病毒VP1抗体
Alias	foot and mouth disease virus; Foot-and-mouth disease virus-type O; Foot-and-mouth disease virus-type Asia 1; Foot-and-mouth disease virus-type Asia 1; Foot-and-mouth disease virus-type C; VP1 protein; FMDV Polyprotein (VP1 protein).
Research Area	Bacteria and viruses
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	FMDV
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	240kDa
Form	Liquid
Concentration	1mg/ml
immunogen	Recombinant FMDV Asia1 VP1 (His tag)
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	The foot-and-mouth disease virus (FMDV) is the pathogen that causes foot-and-mouth disease. It is a picornavirus, the prototypical member of the Aphthovirus genus. The disease, which causes vesicles (blisters) in the mouth and feet of bovids, suids, ovids, caprids and other cloven-hoofed animals is highly infectious and a major plague of animal farming. The virus particle (25-30 nm) has an icosahedral capsid made of protein, without envelope, containing a single strand of ribonucleic acid (RNA) containing a positive encoding of its genome. When the virus comes in contact with the membrane of a host cell, it binds to a receptor site and triggers a folding-in of the membrane. Once the virus is inside the host cell, the capsid dissolves, and the RNA gets replicated, and translated into viral proteins by the cell's ribosomes using a cap-independent mechanism driven by the internal ribosome entry site element. The foot-and-mouth disease virus occurs in seven major serotypes: O, A, C, SAT-1, SAT-2, SAT-3, and Asia-1. These serotypes show some regionality, and the O serotype is most common. Subcellular Location: Host cytoplasm. SWISS: N/A Gene ID: N/A
Product Picture	Sample: Lane 1: Recombinant FMDV VP1 protein, Sumo & His(SL10815P) Lane 2: Recombinant FMDV VP1 (type O) protein, Sumo & His(SL41028P) Lane 3: Recombinant FMDV VP1 (type O) protein, Sumo & His(SL41049P) Primary: Anti-FMDV VP1 (SL10815R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 240 kDa Observed band size: 45 kDa

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