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Product Name Perilipin-2 Chinese Name 脂肪分化相关蛋白抗体 Alias ADFP; Adipophilin; Adipose differentiation related protein; Adipose differentiation-related protein; ADRP; MGC10598; PLIN2; PLIN2_HUMAN. Research Area Tumour Cardiovascular Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species Human, Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-F=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 48kDa Cellular localization The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human ADFP: 341-437/437 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011]
Function:
May be involved in development and maintenance of adipose tissue.
Subcellular Location:
Membrane; Peripheral membrane protein.
Tissue Specificity:
Milk lipid globules.
Post-translational modifications:
Acylated; primarily with C14, C16 and C18 fatty acids.
Similarity:
Belongs to the perilipin family.
SWISS:
Q99541
Gene ID:
123
Database links:Entrez Gene: 123 Human
Entrez Gene: 11520 Mouse
Omim: 103195 Human
SwissProt: Q99541 Human
SwissProt: P43883 Mouse
Unigene: 3416 Human
Unigene: 381 Mouse
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