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Product Name TM9SF1 Chinese Name Transmembrane protein超家族9-1抗体 Alias HMP 70; HMP70; MP 70; MP70; Multispanning membrane protein (70kD); Transmembrane 9 superfamily member 1; Transmembrane protein 9 superfamily member 1; TM9S1_HUMAN. literatures Specific References (1) | SL10764R has been referenced in 1 publications.[IF=10.849] Zhuo, Wei. et al. m6Am methyltransferase PCIF1 is essential for aggressiveness of gastric cancer cells by inhibiting TM9SF1 mRNA translation. CELL DISCOV. 2022 May;8(1):1-17 WB,IHC ; Human,Mouse.Research Area Tumour immunology The cell membrane受体 Immunogen Species Rabbit Clonality Polyclonal React Species Human, Mouse, (predicted: Rat, Dog, Cow, Horse, Rabbit, Sheep, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 66kDa Cellular localization cytoplasmic The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human TM9SF1: 51-150/606 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail TM9SF1 (Transmembrane 9 superfamily member 1) may function as a channel, small molecule transporter or receptor.
Function:
Plays an essential role in autophagy.
Subcellular Location:
Lysosome membrane; Multi-pass membrane protein. Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein.
Tissue Specificity:
Expressed in lung, pancreas, kidney, liver, placenta, skeletal muscle, heart and brain. The amount in skeletal muscle, heart and brain were considerably lower than in the other tissues.
Similarity:
Belongs to the nonaspanin (TM9SF) family.
SWISS:
O15321
Gene ID:
10548
Database links:
Entrez Gene: 10548 Human
Entrez Gene: 74140 Mouse
SwissProt: O15321 Human
SwissProt: Q9DBU0 Mouse
SwissProt: Q5R8F1 Orangutan
Unigene: 91586 Human
Unigene: 132857 Mouse
Unigene: 12071 Rat
Product Picture Sample:
Lane 1: Human Jurkat cell lysates
Lane 2: Human MCF-7 cell lysates
Primary: Anti-TM9SF1 (SL10764R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 66 kDa
Observed band size: 70 kDa
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