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Rabbit Anti-TM9SF1 antibody
Rabbit Anti-TM9SF1 antibody
HMP 70; HMP70; MP 70; MP70; Multispanning membrane protein (70kD); Transmembrane 9 superfamily member 1; Transmembrane protein 9 superfamily member 1; TM9S1_HUMAN.
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  • NO.:SL10764R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Human,Mouse,(predicted: Rat,Dog,Cow,Horse,Rabbit,Sheep,)
    Applications:WB ELISA IHC-P IHC-F ICC IF
    concentration:1mg/ml
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Details

Product Name TM9SF1
Chinese Name Transmembrane protein超家族9-1抗体
Alias HMP 70; HMP70; MP 70; MP70; Multispanning membrane protein (70kD); Transmembrane 9 superfamily member 1; Transmembrane protein 9 superfamily member 1; TM9S1_HUMAN.  
literatures
Specific References  (1)     |     SL10764R has been referenced in 1 publications.
[IF=10.849] Zhuo, Wei. et al. m6Am methyltransferase PCIF1 is essential for aggressiveness of gastric cancer cells by inhibiting TM9SF1 mRNA translation. CELL DISCOV. 2022 May;8(1):1-17  WB,IHC ;  Human,Mouse.  
Research Area Tumour  immunology  The cell membrane受体  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human, Mouse,  (predicted: Rat, Dog, Cow, Horse, Rabbit, Sheep, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 66kDa
Cellular localization cytoplasmic The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human TM9SF1: 51-150/606 
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail TM9SF1 (Transmembrane 9 superfamily member 1) may function as a channel, small molecule transporter or receptor.

Function:
Plays an essential role in autophagy.

Subcellular Location:
Lysosome membrane; Multi-pass membrane protein. Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed in lung, pancreas, kidney, liver, placenta, skeletal muscle, heart and brain. The amount in skeletal muscle, heart and brain were considerably lower than in the other tissues.

Similarity:
Belongs to the nonaspanin (TM9SF) family.

SWISS:
O15321

Gene ID:
10548

Database links:

Entrez Gene: 480261 Dog

Entrez Gene: 10548 Human

Entrez Gene: 74140 Mouse

Entrez Gene: 361043 Rat

SwissProt: A4IFE9 Cow

SwissProt: O15321 Human

SwissProt: Q9DBU0 Mouse

SwissProt: Q5R8F1 Orangutan

SwissProt: Q66HF2 Rat

Unigene: 91586 Human

Unigene: 132857 Mouse

Unigene: 12071 Rat



Product Picture
Sample:
Lane 1: Human Jurkat cell lysates
Lane 2: Human MCF-7 cell lysates
Primary: Anti-TM9SF1 (SL10764R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 66 kDa
Observed band size: 70 kDa
Sample:
Kidney (Mouse) Lysate at 40 ug
Primary: Anti- TM9SF1 (SL10764R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 66 kD
Observed band size: 66 kD

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