Product Name	STAC
Chinese Name	STAC1蛋白抗体
Alias	SH3 and cysteine rich domain; SH3 and cysteine rich domain containing protein; SRC homology 3 and cysteine rich domain protein; Src homology three (SH3) and cysteine rich domain; STAC 1; STAC1; STAC-1; FLJ32331; STAC_HUMAN.
Research Area	Neurobiology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	45kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human STAC: 21-120/402
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	STAC is a 402 amino acid protein that contains one SH3 (Src homology 3) domain and one cysteine-rich domain (CRD). Expressed in brain, STAC is a neuron-specific protein that localizes to the cytoplasm and, based on the frequent involvement of SH3 and CRD domains in signal transduction, is believed to play a role in neuron-specific signal transduction. In addition, STAC may be involved in protecting cells from apoptosis. Due to its neuron-specific expression and putative role in signal transduction, STAC may be implicated in a variety of hereditary neurological diseases. Function: Probably involved in a neuron-specific signal transduction. Subcellular Location: Cytoplasmic. Similarity: Contains 1 phorbol-ester/DAG-type zinc finger. Contains 1 SH3 domain. SWISS: Q99469 Gene ID: 6769 Database links: Entrez Gene: 6769 Human Entrez Gene: 20840 Mouse Entrez Gene: 363152 Rat Omim: 602317 Human SwissProt: Q99469 Human SwissProt: P97306 Mouse Unigene: 56045 Human Unigene: 1414 Mouse

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