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Product Name RAP1GDS1 Chinese Name G蛋白GTP-GDP解离刺激因子1抗体 Alias Exchange factor smgGDS; GDS1; GTP-GDP dissociation stimulator 1; Highly similar to RAP1 GTPASE-GDP DISSOCIATION STIMULATOR 1; RAP1; Rap1 GTPase-GDP dissociation stimulator 1; SMG GDS protein; SMG P21 stimulatory GDP/GTP exchange protein; GDS1_HUMAN. Research Area Tumour Cell biology immunology Signal transduction G protein-coupled receptor Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Cow, Sheep, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 66kDa Cellular localization cytoplasmic Extracellular matrix Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human RAP1GDS1: 511-607/607 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail RAP1GDS1 enhances GDP/GTP exchange reaction in a group of small GTP-binding proteins such as Rap1a/Rap1b, RhoA, RhoB and KRas, by stimulating the dissociation of GDP from each G protein and the subsequent binding of GTP. There are two known isoforms.
Function:
Stimulates GDP/GTP exchange reaction of a group of small GTP-binding proteins (G proteins) including Rap1a/Rap1b, RhoA, RhoB and KRas, by stimulating the dissociation of GDP from and the subsequent binding of GTP to each small G protein.
Similarity:
Contains 5 ARM repeats.
SWISS:
P52306
Gene ID:
5910
Database links:Entrez Gene: 5910 Human
Entrez Gene: 229877 Mouse
Omim: 179502 Human
SwissProt: P52306 Human
Unigene: 132858 Human
Unigene: 28893 Mouse
Uigene: 160647 Rat
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