Product Name	SLC19A2
Chinese Name	SLC19A2抗体
Alias	Thiamine transporter 1; S19A2_HUMAN; SLC19A2; Solute carrier family 19 member 2; TC1; Thiamine carrier 1; THT1; ThTr 1; ThTr-1; ThTr1; TRMA.
Research Area	Tumour  Signal transduction  The new supersedes the old
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	55kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human SLC19A2: 21-120/497 <Extracellular>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	This gene encodes the thiamin transporter protein. Mutations in this gene cause thiamin-responsive megaloblastic anemia syndrome (TRMA), which is an autosomal recessive disorder characterized by diabetes mellitus, megaloblastic anemia and sensorineural deafness. [provided by RefSeq, Jul 2008] Function: High-affinity transporter for the intake of thiamine. Subcellular Location: Membrane. Tissue Specificity: Ubiquitous; most abundant in skeletal and cardiac muscle. Medium expression in placenta, heart, liver and kidney, low in lung. DISEASE: Defects in SLC19A2 are the cause of thiamine-responsive megaloblastic anemia syndrome (TRMA) [MIM:249270]; also known as Rogers syndrome. TRMA is an autosomal recessive disease with features that include megaloblastic anemia, mild thrombocytopenia and leucopenia, sensorineural deafness and diabetes mellitus. Similarity: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family. SWISS: O60779 Gene ID: 10560 Database links: Entrez Gene: 10560 Human Entrez Gene: 116914 Mouse Entrez Gene: 289175 Rat Omim: 603941 Human SwissProt: O60779 Human SwissProt: Q9EQN9 Mouse SwissProt: Q499Q0 Rat Unigene: 30246 Human

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