Product Name	DARC
Chinese Name	Duffy血型Chemokine受体抗体
Alias	CCBP1; CD234; CD234 antigen; DARC; Dfy; Duffy antigen/chemokine receptor; Duffy blood group; DUFFY_MOUSE; FY antibody Fy glycoprotein; Glycoprotein D; GPD; GpFy; Human Duffy blood group antigen (Fya-b+) mRNA complete cds; Plasmodium vivax receptor; WBCQ1; DUFFY_MOUSE.
Research Area	Cardiovascular  Cell biology  immunology  transcriptional regulatory factor  Chemokine  G protein signal
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human, Rat,
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	37kDa
Cellular localization	The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human DARC: 61-150/336 <Extracellular>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Non-specific receptor for many chemokines such as IL-8, GRO, RANTES, MCP-1 and TARC. It is also the receptor for the human malaria parasites Plasmodium vivax and Plasmodium knowlesi. Function: Non-specific receptor for many chemokines. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in liver and brain. Similarity: Belongs to the G-protein coupled receptor Duffy family. SWISS: Q16570 Gene ID: 2532 Database links: Entrez Gene: 2532 Human Entrez Gene: 13349 Mouse Entrez Gene: 681489 Rat Omim: 110700 Human SwissProt: Q16570 Human SwissProt: Q9QUI6 Mouse Unigene: 153381 Human Unigene: 6393 Mouse
Product Picture	Tissue/cell: human lung carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-DARC Polyclonal Antibody, Unconjugated(SL10711R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining Tissue/cell: Rat colon tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-DARC Polyclonal Antibody, Unconjugated(SL10711R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

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