Product Name	GRP
Chinese Name	半乳糖凝集素相关蛋白GRP抗体
Alias	LGALSL; LEGL_HUMAN; Galectin-related protein; Lectin galactoside-binding-like protein; HSPC159.
Research Area	Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, )
Applications	ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Cellular localization	Extracellular matrix
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human GRP: 1-100/172
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Galectins are a family of soluble b-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and also play a role in tumor progression, pre-mRNA splicing and apoptosis. The Galectin-related protein (GRP), also designated HSPC159, is a 172 amino acid protein that contains one galectin domain. However, HSPC159 does not appear to bind carbohydrates or lactose because the critical residues required for binding are not conserved. The gene encoding HSPC159 maps to human chromosome 2, which consists of 237 million bases and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2, including Harlequin icthyosis, sitosterolemia and Alstr鰉 syndrome. Function: Does not bind lactose, and may not bind carbohydrates. Subunit: Monomer (Probable). Similarity: Contains 1 galectin domain. SWISS: Q3ZCW2 Gene ID: 29094 Database links: Entrez Gene: 470387 Chimpanzee Entrez Gene: 516629 Cow Entrez Gene: 101141454 Gorilla Entrez Gene: 29094 Human Entrez Gene: 216551 Mouse Entrez Gene: 360983 Rat SwissProt: Q3ZCW2 Human SwissProt: Q8VED9 Mouse SwissProt: Q5R5K6 Orangutan Unigene: 372208 Human

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