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Product Name TRH Chinese Name 促甲状腺素释放激素抗体 Alias Pro-thyrotropin-releasing hormone; Pro-TRH; Prothyroliberin; Thyrotropin-releasing hormone; TRH; Protirelin; TSH-releasing factor; Thyroliberin; Thyrotropin-releasing factor; TRF; TRH_HUMAN. Research Area Tumour Neurobiology Signal transduction Growth factors and hormones Endocrinopathy The new supersedes the old Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, ) Applications ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 24kDa Cellular localization Secretory protein Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide TRH (pGlu-His-Pro-Amide): 101-200/242 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail This gene encodes a member of the thyrotropin-releasing hormone family. Cleavage of the encoded proprotein releases mature thyrotropin-releasing hormone, which is a tripeptide hypothalamic regulatory hormone. The human proprotein contains six thyrotropin-releasing hormone tripeptides. Thyrotropin-releasing hormone is involved in the regulation and release of thyroid-stimulating hormone, as well as prolactin. Deficiency of this hormone has been associated with hypothalamic hypothyroidism. [provided by RefSeq, May 2013].
(L-Pyroglutamyl-L-histidyl-L-prolinamide)pGlu-His-Pro Amide, C18H26N6O6
Function:
Thyrotropin releasing hormone (TRH) is a tripeptide hormone that stimulates the release of thyroid stimulating hormone and prolactin by the anterior pituitary. TRH is produced by the hypothalamus and travels across the median eminence to the pituitary via the hypophyseal portal system. In addition to the brain, TRH can also be detected in other areas of the body including the gastrointestinal system and pancreatic islets.
Subcellular Location:
Secreted.
Tissue Specificity:
Hypothalamus. Expressed in the hair follicle epithelium (at protein level).
Similarity:
Belongs to the TRH family.
SWISS:
P20396
Gene ID:
7200
Database links:Entrez Gene: 7200 Human
Entrez Gene: 22044 Mouse
Omim: 275120 Human
SwissProt: P20396 Human
SwissProt: Q62361 Mouse
Unigene: 1363 Mouse
Unigene: 22 Rat
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