Product Name	CCP
Chinese Name	瓜氨酸环肽抗体
Alias	cyclic citrullinated peptide.
literatures	Specific References  (6)     |     SL1053R has been referenced in 6 publications. [IF=7.78] Zhou,et al.Ultrasensitive label-free optical microfiber coupler biosensor for detection of cardiac troponin I based on interference turning point effect.(2018) Biosensors & Bioelectronics. 106:99-104.  Other ;   PubMed:29414096 [IF=3.519] Tomomi Sato et al. Citrullinated fibrinogen is a target of autoantibodies in interstitial lung disease in mice with collagen-induced arthritis. Int Immunol . 2020 Jul 28;32(8):533-545.  IF ;  mouse.   PubMed:32239143 [IF=3.275] R S et al. Electrochemical Immunosensor for the Early Detection of Rheumatoid Arthritis Biomarker: Anti-Cyclic Citrullinated Peptide Antibody in Human Serum Based on Avidin-Biotin SystemSensors (Basel).2020 Dec28;21(1):124.  other ;   PubMed:33379138 [IF=3.15] Gertel,et al.Anticitrullinated Protein Antibodies Induce Inflammatory Gene Expression Profile in Peripheral Blood Cells from CCP-positive Patients with RA.(2018) The Journal of Rheumatology. 45:310-319.  Other ;  Human.   PubMed:29335340 [IF=2.878] Arita S et al. Peptidylarginine deiminase is involved in maintaining the cornified oral mucosa of rats.J Periodontal Res. 2018 Oct;53(5):750-761.  IHC-P&WB ;  Rat.   PubMed:29687476 [IF=1.26] Sun et al. Effects of forced swimming stress on thyroid function, pituitary thyroid-stimulating hormone and hypothalamus thyrotropin releasing hormone expression in adrenalectomy Wistar rats. (2016) Exp.Ther.Me. 12:3167-3174  IHC ;  Rat.   PubMed:27882133
Research Area	immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
Applications	WB=1:500-2000 ELISA=1:5000-10000  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	2.34kDa
Cellular localization	cytoplasmic
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide of CCP
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	以高纯度合成的环瓜氨酸多肽为抗原，制备的抗CCP环肽的抗体；环瓜氨酸肽(CCP)抗体对类风湿性关节炎诊断的敏感性和特异性很高,CCP抗体目前主要用于对类风湿性关节炎的早期诊断和治疗后的评估上。 高纯度合成的环瓜氨酸多肽为抗原，检测血清中的抗环瓜氨酸多肽抗体，对于RA的诊断具有很高的价值。抗环瓜氨酸肽抗体的敏感性在患病人群中的特异性为97%。

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