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Rabbit Anti-VAMP1+VAMP2+VAMP3 antibody
Rabbit Anti-VAMP1+VAMP2+VAMP3 antibody
VAMP-1+2+3; Vesicle Associated Membrane Protein 1; DKFZp686H12131; SYB 1; SYB1; Synaptobrevin 1; Synaptobrevin1; Synaptobrevin-1; VAMP 1; VAMP-1; Vesicle associated membrane protein 1; Vesicle associated membrane protein 1 synaptobrevin 1; VAMP1_HUMAN; Ve
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  • NO.:SL10427R
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep,Guinea Pig,)
    Applications:WB ELISA IHC-F ICC IF
    concentration:1mg/ml
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Product Name VAMP1+VAMP2+VAMP3
Chinese Name 囊泡相关膜蛋白1,2,3抗体
Alias VAMP-1+2+3; Vesicle Associated Membrane Protein 1; DKFZp686H12131; SYB 1; SYB1; Synaptobrevin 1; Synaptobrevin1; Synaptobrevin-1; VAMP 1; VAMP-1; Vesicle associated membrane protein 1; Vesicle associated membrane protein 1 synaptobrevin 1; VAMP1_HUMAN; Vesicle-associated membrane protein 1; Vesicle Associated Membrane Protein 2; FLJ11460; RATVAMPB; RATVAMPIR; SYB; SYB2; Synaptobrevin 2; VAMP 2; VAMP-2; Vesicle associated membrane protein 2; Vesicle-associated membrane protein 2; VAMP2_HUMAN; Synaptobrevin-2; Vesicle Associated Membrane Protein 3; VAMP-3; VAMP 3; VAMP3; CEB; Cellubrevin; Synaptobrevin 3; Synaptobrevin-3; MGC108618; Vamp3; D130027G05Rik; VAMP3_HUMAN; Vesicle-associated membrane protein 3.  
Research Area Tumour  Cell biology  Neurobiology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, )
Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight 13/11kDa
Cellular localization cytoplasmic The cell membrane 
Form Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human VAMP-1+2+3: 21-118/118 <Cytoplasmic>
Lsotype IgG
Purification affinity purified by Protein A
Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
Product Detail Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation. [provided by RefSeq, Jul 2008].

Function:
SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network.

Subunit:
Interacts with VAPA and VAPB.

Subcellular Location:
Membrane; Single-pass type IV membrane protein (Probable). Cell junction, synapse, synaptosome.

Tissue Specificity:
Nervous system, skeletal muscle and adipose tissue.

Similarity:
Belongs to the synaptobrevin family.
Contains 1 v-SNARE coiled-coil homology domain.

SWISS:
P23763

Gene ID:
6843

Database links:

Entrez Gene: 6843 Human

Entrez Gene: 6844 Human

Entrez Gene: 9341 Human

Entrez Gene: 22317 Mouse

Entrez Gene: 22318 Mouse

Entrez Gene: 22319 Mouse

Entrez Gene: 24803 Rat

Entrez Gene: 25624 Rat

Entrez Gene: 29528 Rat

Omim: 185880 Human

Omim: 185881 Human

Omim: 603657 Human

SwissProt: P23763 Human

SwissProt: P63027 Human

SwissProt: Q15836 Human

SwissProt: P63024 Mouse

SwissProt: P63044 Mouse

SwissProt: Q62442 Mouse

SwissProt: P63025 Rat

SwissProt: P63045 Rat

SwissProt: Q63666 Rat

Unigene: 20021 Human

Unigene: 25348 Human

Unigene: 66708 Human

Unigene: 273930 Mouse

Unigene: 28643 Mouse

Unigene: 32321 Mouse

Unigene: 12939 Rat

Unigene: 219999 Rat

Unigene: 31977 Rat



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