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Product Name VAMP1+VAMP2+VAMP3 Chinese Name 囊泡相关膜蛋白1,2,3抗体 Alias VAMP-1+2+3; Vesicle Associated Membrane Protein 1; DKFZp686H12131; SYB 1; SYB1; Synaptobrevin 1; Synaptobrevin1; Synaptobrevin-1; VAMP 1; VAMP-1; Vesicle associated membrane protein 1; Vesicle associated membrane protein 1 synaptobrevin 1; VAMP1_HUMAN; Vesicle-associated membrane protein 1; Vesicle Associated Membrane Protein 2; FLJ11460; RATVAMPB; RATVAMPIR; SYB; SYB2; Synaptobrevin 2; VAMP 2; VAMP-2; Vesicle associated membrane protein 2; Vesicle-associated membrane protein 2; VAMP2_HUMAN; Synaptobrevin-2; Vesicle Associated Membrane Protein 3; VAMP-3; VAMP 3; VAMP3; CEB; Cellubrevin; Synaptobrevin 3; Synaptobrevin-3; MGC108618; Vamp3; D130027G05Rik; VAMP3_HUMAN; Vesicle-associated membrane protein 3. Research Area Tumour Cell biology Neurobiology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, ) Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 13/11kDa Cellular localization cytoplasmic The cell membrane Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human VAMP-1+2+3: 21-118/118 <Cytoplasmic> Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation. [provided by RefSeq, Jul 2008].
Function:
SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network.
Subunit:
Interacts with VAPA and VAPB.
Subcellular Location:
Membrane; Single-pass type IV membrane protein (Probable). Cell junction, synapse, synaptosome.
Tissue Specificity:
Nervous system, skeletal muscle and adipose tissue.
Similarity:
Belongs to the synaptobrevin family.
Contains 1 v-SNARE coiled-coil homology domain.
SWISS:
P23763
Gene ID:
6843
Database links:Entrez Gene: 6843 Human
Entrez Gene: 6844 Human
Entrez Gene: 9341 Human
Entrez Gene: 22317 Mouse
Entrez Gene: 22318 Mouse
Entrez Gene: 22319 Mouse
Omim: 185880 Human
Omim: 185881 Human
Omim: 603657 Human
SwissProt: P23763 Human
SwissProt: P63027 Human
SwissProt: Q15836 Human
SwissProt: P63024 Mouse
SwissProt: P63044 Mouse
SwissProt: Q62442 Mouse
Unigene: 20021 Human
Unigene: 25348 Human
Unigene: 66708 Human
Unigene: 273930 Mouse
Unigene: 28643 Mouse
Unigene: 32321 Mouse
Unigene: 12939 Rat
Unigene: 219999 Rat
Unigene: 31977 Rat
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