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Product Name H3N7 hemagglutinin Chinese Name 流感病毒H3N7血凝素抗体 Alias HA; Influenza A virus H3N7; hemagglutinin; H3N7; H3N7 hemagglutinin; Hemagglutinin HA1 chain; Hemagglutinin HA2 chain; C0RVD1_9INFA. Immunogen Species Rabbit Clonality Polyclonal Applications WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (Paraffin sections need antigen repair)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Theoretical molecular weight 63kDa Form Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from H3N7 hemagglutinin: 465-566/566 Lsotype IgG Purification affinity purified by Protein A Buffer Solution 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. Attention This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. PubMed PubMed Product Detail Hemagglutinin (HA) is a class I viral fusion protein from Influenza virus. It is a major glycoprotein, comprising over 80% of the envelope proteins present in the virus particle. HA binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell, and is responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. The extent of infection into host organism is determined by HA. In natural infection, inactive HA is matured into HA1 and HA2 outside the cell by one or more trypsin-like, arginine-specific endoproteases secreted by the bronchial epithelial cells. The HA protein is a homotrimer of disulfide-linked HA1-HA2. It also plays a major role in the determination of host range restriction and virulence. Genetic variation of hemagglutinin and/or neuraminidase genes results in the emergence of new influenza strains.
Subunit:
Homotrimer of disulfide-linked HA1-HA2.
Subcellular Location:
Cell membrane; apical cell membrane; single-pass type I membrane protein.
Similarity:
Belongs to the influenza viruses hemagglutinin family.
SWISS:
N/A
Gene ID:
N/A
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