Product Name	TRPV2
Chinese Name	辣椒素受体样蛋白1抗体
Alias	Osm 9 like TRP channel 2; Osm-9-like TRP channel 2; OTRPC2; Sac2b; Stretch activated channel 2B; Transient receptor potential cation channel subfamily V member 2; TrpV2; TRPV2_HUMAN; Vanilloid receptor like protein 1; Vanilloid receptor-like protein 1; VRL 1; VRL; VRL-1; VRL1.
literatures	Specific References  (3)     |     SL10297R has been referenced in 3 publications. [IF=4.014] Zhi Wang. et al. Differential expressions of hypothalamic thermosensitive TRP ion channels may underlie the post-hatching ontogeny of brain cooling capacity in broiler chickens. POULTRY SCIENCE. 2023 May;:102782  WB ;  Chicken.   PubMed:37276706 [IF=3.642] Ming-Chuang Sun. et al. ETV5 overexpression promotes progression of esophageal squamous cell carcinoma by upregulating SKA1 and TRPV2. INT J MED SCI. 2022; 19(6): 1072–1081  WB ;  Human.   PubMed:35813298 [IF=2.276] Zhao Wei. et al. Tetrandrine Ameliorates Myocardial Ischemia Reperfusion Injury through miR-202-5p/TRPV2. Biomed Res Int. 2021;2021:8870674  WB,IHC ;  Rat.   PubMed:33763489
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （Paraffin sections need antigen repair） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Theoretical molecular weight	86kDa
Cellular localization	cytoplasmic The cell membrane
Form	Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human TRPV2: 601-700/764 <Cytoplasmic>
Lsotype	IgG
Purification	affinity purified by Protein A
Buffer Solution	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300.
Storage	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Attention	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
Product Detail	Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH. Function: Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH. Subunit: Homotetramer. Subcellular Location: Cell membrane; Multi-pass membrane protein. Cytoplasm. Melanosome. Post-translational modifications: N-glycosylated. Phosphorylated by PKA. Similarity: Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV2 sub-subfamily. Contains 6 ANK repeats. SWISS: Q9Y5S1 Gene ID: 51393 Database links: Entrez Gene: 51393 Human Omim: 606676 Human SwissProt: Q9Y5S1 Human Unigene: 279746 Human

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